Research advances on transgenic plant vaccines.

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Research advances on transgenic plant vaccines. Abstract Text:

Mei Han,Tao Su,Yuan-Gang Zu,Zhi-Gang An,

In recent years, with the development of genetics molecular biology and plant biotechnology, the vaccination (e.g. genetic engineering subunit vaccine, living vector vaccine, nucleic acid vaccine) programs are taking on a prosperous evolvement. In particular, the technology of the use of transgenic plants to produce human or animal therapeutic vaccines receives increasing attention. Expressing vaccine candidates in vegetables and fruits open up a new avenue for producing oral/edible vaccines. Transgenic plant vaccine disquisitions exhibit a tempting latent exploiting foreground. There are a lot of advantages for transgenic plant vaccines, such as low cost, easiness of storage, and convenient immune-inoculation. Some productions converged in edible tissues, so they can be consumed directly without isolation and purification. Up to now, many transgenic plant vaccine productions have been investigated and developed. In this review, recent advances on plant-derived recombinant protein expression systems, infectious targets, and delivery systems are presented. Some issues of high concern such as biosafety and public health are also discussed. Special attention is given to the prospects and limitations on transgenic plant vaccines.

Research advances on transgenic plant vaccines. Publishing Authors By Initials

M Han,T Su,YG Zu,ZG An,

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Research advances on transgenic plant vaccines. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Yi chuan xue bao = Acta genetica Sinica

VOLUME: 33

Page Numbers: 285-93

Journal Abbreviation: Yi Chuan Xue Bao

ISSN: 0379-4172

DAY: 21

MONTH: Apr

YEAR: 2006

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LANGUAGE: eng

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AFFILIATION: Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, China.

Country: China

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MEDLINETA: Yi Chuan Xue Bao

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