Reporting of multivariable methods in the medical literature.

Reporting of multivariable methods in the medical literature. Research Abstract Details 

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Reporting of multivariable methods in the medical literature. Abstract Text:

BACKGROUND:: Multivariable models are frequently used in the medical literature, but many clinicians have limited training in these analytic methods. Our objective was to assess the prevalence of multivariable methods in medical literature, quantify reporting of methodological criteria applicable to most methods, and determine if assumptions specific to logistic regression or proportional hazards analysis were evaluated. METHODS:: We examined all original articles in Annals of Internal Medicine, British Medical Journal, Journal of the American Medical Association, Lancet, and New England Journal of Medicine, from January through June 2006. Articles reporting multivariable methods underwent a comprehensive review; reporting of methodological criteria was based on each article's primary analysis. RESULTS:: Among 452 articles, 272 (60%) used multivariable analysis; logistic regression (89 [33%] of 272) and proportional hazards (76 [28%] of 272) were most prominent. Reporting of methodological criteria, when applicable, ranged from 5% (12/265) for assessing influential observations to 84% (222/265) for description of variable coding. Discussion of interpreting odds ratios occurred in 13% (12/89) of articles reporting logistic regression as the primary method and discussion of the proportional hazards assumption occurred in 21% (16/76) of articles using Cox proportional hazards as the primary method. CONCLUSIONS:: More complete reporting of multivariable analysis in the medical literature can improve understanding, interpretation, and perhaps application of these methods.

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Reporting of multivariable methods in the medical literature. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of investigative medicine : the official p

VOLUME: 56

Page Numbers: 954-7

Journal Abbreviation: J. Investig. Med.

ISSN: 1081-5589

DAY: 3

MONTH: Oct

YEAR: 2008

Reporting of multivariable methods in the medical literature. Information

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LANGUAGE: eng

NlmUniqueID: 9501229

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AFFILIATION: From the Veterans Affairs Clinical Epidemiology Research Center,West Haven; and Yale University School of Medicine, New Haven, CT.

Country: Canada

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MEDLINETA: J Investig Med

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