We developed mathematical modeling tools for mapping 3D infarct geometry from multislice late gadolinium enhancement data, allowing fusion with multislice MR tagging data, in mice with myocardial infarction. Five C57BL/6 mice were imaged at baseline, 1, 7 and 28 days after 60 min occlusion of the left anterior descending coronary artery. The 3D infarct geometry was mapped in material coordinates, and registered with 3D strain, showing permanent dysfunction in infarcted segments, intermediate function in the adjacent zone, and maintained function in the remote zone. 3D mapping of late enhancement and strain allows registration of multiple studies in a consistent framework.
Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain. Publishing Authors By Initials
Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Journal of cardiovascular magnetic resonance : off
VOLUME: 8
Page Numbers: 685-92
Journal Abbreviation:
ISSN: 1097-6647
DAY: 3
MONTH: 12
YEAR: 2006
Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 9815616
Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain. Keywords Mesh Terms:
KEYWORDS:
MESH TERMS:
Chemical & Substance for Abstract: Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain. Information
Substance Name:
Registry Number:
Grant and Affiliation Information for Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain.
AFFILIATION: Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. a.young@auckland.ac.nz
Country: United States
AGENCY:
GRANT:
ACRONYM:
MEDLINETA: J Cardiovasc Magn Reson
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain Related Publications