Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities.

Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities. Research Abstract Details 

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Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities. Abstract Text:

Ronge Xing,Song Liu,Zhanyong Guo,Huahua Yu,Zhimei Zhong,Xia Ji,Pengcheng Li,

The antioxidant potency of high/low molecular weight quaternary chitosan derivatives was investigated employing various established systems in vitro, such as superoxide (O(2)(-)) and hydroxyl (OH) radicals scavenging, reducing power and iron ion chelating. As expected, we obtained several satisfying results, as follow: firstly, low molecular weight quaternary chitosan had stronger scavenging effect on O(2)(-) and OH than high molecular weight quaternary chitosan. Secondly, the reducing power of low molecular weight quaternary chitosan was more pronounced than that of high molecular weight quaternary chitosan. Thirdly, ferrous ion chelating potency were showed to increase first and decrease afterwards with increasing concentration for two kinds of quaternary chitosans, namely, they have not concentration-dependence. However, the scavenging rate and reducing power of high and low molecular weight quaternary chitosans increased with their increasing concentrations, and hence were concentration-dependent.

Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities. Publishing Authors By Initials

R Xing,S Liu,Z Guo,H Yu,Z Zhong,X Ji,P Li,

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Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of medicinal chemistry

VOLUME: 43

Page Numbers: 336-40

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ISSN: 0223-5234

DAY: 7

MONTH: 04

YEAR: 2007

Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Relevance of molecular weight of chitosan-N-2-hydroxypropyl trimethyl ammonium chloride and their antioxidant activities.

AFFILIATION: Institute of Oceanology, The Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.

Country: France

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MEDLINETA: Eur J Med Chem

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