Relationship of HLA to major affective disorder not supported.

Relationship of HLA to major affective disorder not supported. Research Abstract Details 

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Relationship of HLA to major affective disorder not supported. Abstract Text:

A recently published report (Weitkamp et al., 1981) concludes that a major susceptibility locus for depression is located in the HLA region of chromosome 6. This conclusion was based on increased sharing of HLA haplotypes in affected sib pairs and nonrandom segregation of HLA types and illness in families. However, both of these findings were true only for specific subsamples of the data. Here, we suggest that the criteria used to subdivide the data are not theoretically justified. In addition, we show that we cannot replicate their findings in our own new data. Our data do not support any relationship of HLA type to affective disorders.

Relationship of HLA to major affective disorder not supported. Publishing Authors By Initials

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk research

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Relationship of HLA to major affective disorder not supported. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 7

Page Numbers: 29-45

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Aug

YEAR: 1982

Relationship of HLA to major affective disorder not supported. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Relationship of HLA to major affective disorder not supported. Keywords Mesh Terms:

KEYWORDS: Risk

MESH TERMS: genetics

Chemical & Substance for Abstract: Relationship of HLA to major affective disorder not supported. Information

Substance Name: HLA Antigens

Registry Number: 0

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Country: NETHERLANDS

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MEDLINETA: Psychiatry Res

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