Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons.

Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Research Abstract Details 

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Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Abstract Text:

P Ashby,D Zilm,

We used a computer model (making several simplifying assumptions) to explore the relationship between the characteristics of an excitatory postsynaptic potential (EPSP) and the profile of the change in firing probability that occurred when that EPSP was delivered to a rhythmically discharging neuron. In circumstances applicable to studies on human motoneurons we found that the magnitude of the period of increased firing probability in the cross-correlation (produced by the rising phase of the EPSP) was related to the number of stimuli and to the proportion of the interspike interval that the EPSP was within reach of threshold. The interstimulus interval and the statistical distribution of the motoneuron interspike intervals were of little consequence. For this model the subsequent period of reduced firing probability was proportional to the amplitude of the EPSP and not to the duration of its falling phase.

Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Publishing Authors By Initials

P Ashby,D Zilm,

For similar synaptic transmission research abstracts see: synaptic transmission research

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Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 47

Page Numbers: 33-40

Journal Abbreviation:

ISSN: 0014-4819

DAY: 15

MONTH: 02

YEAR: 1982

Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Information

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LANGUAGE: eng

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Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Keywords Mesh Terms:

KEYWORDS: Synaptic Transmission

MESH TERMS: physiology

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Country: GERMANY, WEST

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MEDLINETA: Exp Brain Res

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