Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis.

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Abstract Text:

John A Angelos,Louise M Ball,John A Angelos,Louise M Ball,

To determine whether amino acid sequence variation exists in the Moraxella bovis (M. bovis) cytotoxin (MbxA) from geographically diverse M. bovis isolated in the United States, mbxA was amplified and sequenced. The MbxA deduced amino acid sequence from M. bovis originally isolated in California, Washington, North Carolina, and Georgia, as well as reference strains of M. bovis isolated at the National Animal Disease Laboratory, Ames, IA, USA, all encoded a nearly identical 927 amino acid protein. MbxA from two of the four California isolates (SFS 9a and SFS 100a) differed from all other isolates at two sites at which the polar amino acids glutamine (position 666) and asparagine (position 823) were replaced by ionized amino acids glutamic acid and aspartic acid, respectively. Rabbit antiserum to the expressed carboxy terminus (amino acids 590-927) of MbxA from M. bovis (Tifton I) neutralized the hemolytic activity of SFS 9a and SFS 100a. The M. bovis cytotoxin appears to be conserved amongst geographically diverse isolates of M. bovis from the USA. Antiserum against the carboxy terminus of MbxA common to the majority of isolates neutralized the hemolytic activity of two strains with a divergent MbxA deduced amino acid sequence. Vaccines against IBK that incorporate MbxA as antigen may offer protection against geographically diverse strains of M. bovis.

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Publishing Authors By Initials

JA Angelos,LM Ball,JA Angelos,LM Ball,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Veterinary microbiology

VOLUME: 124

Page Numbers: 382-6

Journal Abbreviation: Vet. Microbiol.

ISSN: 0378-1135

DAY: 3

MONTH: 05

YEAR: 2007

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7705469

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis.

AFFILIATION: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 2108 Tupper Hall, Davis, CA 95616, USA. jaangelos@ucdavis.edu

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Vet Microbiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis Related Publications

• A chimeric human/murine anticocaine monoclonal antibody inhibits the distribution of cocaine to the brain in mice.
• A simple way of securing drains.
• Adverse events experienced by three children taking tenofovir and didanosine in combination.
• Behavioural determinants of the obesity epidemic.
• Characterization of NADPH oxidase 5 in equine testis and spermatozoa.
• Comparing individual therapies for personality disordered opioid dependent patients.
• Complexities of expressive word learning over time.
• Cortisol circadian rhythms and stress responses in infants at risk of allergic disease.
• Differentiation of Moraxella bovoculi sp. nov. from other coccoid moraxellae by the use of polymerase chain reaction and restriction endonuclease analysis of amplified DNA.
• Effect of infusion of uterine purulent exudate into the bovine uterus.
• Effects of a controlled diet supplemented with chickpeas on serum lipids, glucose tolerance, satiety and bowel function.
• Effects of olive oil and tomato lycopene combination on heart disease risk factors.
• Evaluation of guided imagery as treatment for recurrent abdominal pain in children: a randomized controlled trial.
• Full-length, glycosylated NSP4 is localized to plasma membrane caveolae by a novel raft isolation technique.
• Generation of superoxide anion by equine spermatozoa as detected by dihydroethidium.
• Hormonal emergency contraception: increasing awareness and access.
• Isolation of Mycoplasma bovis from cattle in Northern Ireland from 1999 to 2005.
• Medullary thyroid cancer: therapeutic targets and molecular markers.
• Meeting report: Fourth Forum on Respiratory Tract Infections, Sitges, Spain, 8 11 February 2007.
• Noradrenergic projections to the song control nucleus area X of the medial striatum in male zebra finches (Taeniopygia guttata).
• Parenteral nutrition using MCT/LCT or LCT: Effect on the fatty acid composition of plasma triglycerides and platelet phospholipids.
• Regulation of estrous cycles in dairy cattle: A review.
• Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis.
• Reversing the slow death of the clinical necropsy: developing the post of the Pathology Liaison Nurse.
• Subjective cognitive function and decline among older adults with psychometrically defined amnestic MCI.
• The Stanford Microarray Database: implementation of new analysis tools and open source release of software.
• Topography in the preoptic region: differential regulation of appetitive and consummatory male sexual behaviors.
• Universal access to HIV/AIDS treatment for injecting drug users: keeping the promise.
• Vasopressin and disorders of water balance: the physiology and pathophysiology of vasopressin.
• Vesicular adenitis of bulls: A review.