Regulatory T cells--the renaissance of the suppressor T cells.

Regulatory T cells--the renaissance of the suppressor T cells. Research Abstract Details 

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Regulatory T cells--the renaissance of the suppressor T cells. Abstract Text:

Tobias Bopp,Helmut Jonuleit,Edgar Schmitt,Tobias Bopp,Helmut Jonuleit,Edgar Schmitt,

Immune reactions are stringently regulated and balanced by complex interactions of stimulating and suppressing mechanisms. Dysfunctions of this sophisticated immune regulatory network can lead to a variety of diseases such as autoimmunity, allergy, cancer, and pregnancy disorders. The rediscovery of suppressor T cells a decade ago--now designated as T regulatory cells--set off a huge avalanche of research activities leading to a multitude of preclinical and clinical studies. Herein, we give a comprehensive review about this research on T regulatory cells and the relevance of this suppressive T cell population for the development of innovative immune therapeutic strategies.

Regulatory T cells--the renaissance of the suppressor T cells. Publishing Authors By Initials

T Bopp,H Jonuleit,E Schmitt,T Bopp,H Jonuleit,E Schmitt,

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Regulatory T cells--the renaissance of the suppressor T cells. Journal Published:

PUBLICATION TYPE: Review

Journal: Annals of medicine

VOLUME: 39

Page Numbers: 322-34

Journal Abbreviation: Ann. Med.

ISSN: 0785-3890

DAY: 16

MONTH: 08

YEAR: 2007

Regulatory T cells--the renaissance of the suppressor T cells. Information

Number of References: 137

LANGUAGE: eng

NlmUniqueID: 8906388

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Grant and Affiliation Information for Regulatory T cells--the renaissance of the suppressor T cells.

AFFILIATION: Department of Dermatology, Johannes Gutenberg-University, Mainz, Germany.

Country: Sweden

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MEDLINETA: Ann Med

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