Regulative feedback in pattern formation: towards a general relativistic theory of positional information.

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Abstract Text:

Positional specification by morphogen gradients is traditionally viewed as a two-step process. A gradient is formed and then interpreted, providing a spatial metric independent of the target tissue, similar to the concept of space in classical mechanics. However, the formation and interpretation of gradients are coupled, dynamic processes. We introduce a conceptual framework for positional specification in which cellular activity feeds back on positional information encoded by gradients, analogous to the feedback between mass-energy distribution and the geometry of space-time in Einstein's general theory of relativity. We discuss how such general relativistic positional information (GRPI) can guide systems-level approaches to pattern formation.

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Development (Cambridge, England)

VOLUME: 135

Page Numbers: 3175-83

Journal Abbreviation: Development

ISSN: 0950-1991

DAY: 8

MONTH: Oct

YEAR: 2008

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8701744

Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Regulative feedback in pattern formation: towards a general relativistic theory of positional information. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Regulative feedback in pattern formation: towards a general relativistic theory of positional information.

AFFILIATION: Laboratory for Development and Evolution, University Museum of Zoology, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Development

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Regulative feedback in pattern formation: towards a general relativistic theory of positional information Related Publications

• A Visual Analogue Scale technique to measure global vigor and affect.
• A curious eruption: erythema gyratum repens in resolving pustular psoriasis.
• Age wise: aging well by sleeping well.
• An efficient screening tool for preoperative depression: the geriatric depression scale-short form.
• Candida albicans drug resistance another way to cope with stress.
• Cervical neoplasia in pregnancy. Part 2: current treatment of invasive disease.
• Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.
• Conference report for the 2(nd) MC-GARD series on "Interplay among genetics, epigenetics and non-coding RNAs".
• Cost-effectiveness of adding human papilloma virus testing to a managed care cervical cancer screening program.
• Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: Can prenatal programming be modified?
• Identifying dynamical modules from genetic regulatory systems: applications to the segment polarity network.
• Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution.
• Injuries of the tibio-fibular ligaments.
• Personality correlates with sleep-wake variables.
• Practical consequences of fatigue-related performance failures.
• Pregnant women's cortisol is elevated with anxiety and depression - but only when comorbid.
• Prenatal predictors of infant temperament.
• Radiographic technique chart.
• Recognition of facial emotions among maltreated children with high rates of post-traumatic stress disorder.
• Regulative feedback in pattern formation: towards a general relativistic theory of positional information.
• Relationship between trait anxiety, prefrontal cortex, and attention bias to angry faces in children and adolescents.
• Single-cell analysis of unstable genes.
• Stress, immunity, and cervical cancer: biobehavioral outcomes of a randomized clinical trail.
• The Pediatrician's Role in Preventing Cervical Cancer.
• The construction of cDNA libraries from human single preimplantation embryos and their use in the study of gene expression during development.
• The flowering of systems approaches in plant and crop biology.
• The lingering death of the autopsy.
• Topical fluorouracil in vitiligo.
• Traumatic ischaemia of the calf.
• Type and severity of cognitive decline in older adults after noncardiac surgery.