Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1.

Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1. Research Abstract Details 

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Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1. Abstract Text:

P Morris,

Cultured leaf discs of CATHARANTHUS ROSEUS produced visible callus under a variety of cultural conditions within 10 to 15 days. A peak of respiratory activity typical of rapidly growing callus was observed after 10-20 days culture. Photosynthesis was inactivated on transferring leaf tissue into culture within 5 days. During this period the two main leaf alkaloids, catharanthine and vindoline, were rapidly metabolised and were not found in primary callus or in the original leaf tissue after 40 days culture. The alkaloids serpentine and ajmalicine accumulated in leaf tissue but predominantly in callus, during the callus induction and growth period. Serpentine was the major alkaloid accumulated in the light and ajmalicine in the dark. Maximal alkaloid accumulation was found with the production media devised by Zenk but sustained callus growth did not occur. Cultures which accumulated high levels of serpentine over repeated subcultures were derived on other media, but these cultures did not contain catharanthine or vindoline.

Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1. Publishing Authors By Initials

P Morris,

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Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Planta medica

VOLUME: 52

Page Numbers: 127-32

Journal Abbreviation: Planta Med.

ISSN: 0032-0943

DAY: 8

MONTH: Apr

YEAR: 1986

Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1. Information

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LANGUAGE: eng

NlmUniqueID: 66751

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Grant and Affiliation Information for Regulation of Product Synthesis in Cell Cultures of Catharanthus roseus. III. Alkaloid Metabolism in Cultured Leaf Tissue and Primary Callus1.

AFFILIATION: Wolfman Institute of Biotechnology, Western Bank, The University, Sheffield S10 2TN, England.

Country: Germany

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MEDLINETA: Planta Med

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