Rectal microbicide acceptability: results of a volume escalation trial.

Rectal microbicide acceptability: results of a volume escalation trial. Research Abstract Details 

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Rectal microbicide acceptability: results of a volume escalation trial. Abstract Text:

Alex ,Theresa Exner,Curtis Dolezal,Robert Pickard,Peter Lin,Kenneth H Mayer,

OBJECTIVES: The objectives of this study were to determine what volume of a microbicide placebo gel is acceptable when applied intrarectally before receptive anal intercourse (RAI); and to evaluate responses to properties of the gel, its application, and its use. STUDY DESIGN: HIV-uninfected men who reported unprotected RAI with serodiscordant or unknown-status partners were enrolled in a volume escalation trial. RESULTS: Up to 35 mL of gel with the physical properties of Femglide (transparent and odorless) was acceptable to the majority of participants. Choice of different levels of viscosity may be needed. For some men, volumes judged acceptable when tried without intercourse were not acceptable when used during sex. Overall, participants reported high intentions to use microbicides when available. Condom use was inconsistent despite advice to use condoms. CONCLUSIONS: Microbicides that would require up to 35 mL of volume to be effective would be acceptable to men who engage in high-risk RAI.

Rectal microbicide acceptability: results of a volume escalation trial. Publishing Authors By Initials

A ,T Exner,C Dolezal,R Pickard,P Lin,KH Mayer,

For similar behavior and behavior mechanisms: behavior: sexual behavior: unsafe sex research abstracts see: behavior and behavior mechanisms: behavior: sexual behavior: unsafe sex research

PUBMED ID PMID:

MEDLINE DATE:

Rectal microbicide acceptability: results of a volume escalation trial. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Sexually transmitted diseases

VOLUME: 34

Page Numbers: 224-9

Journal Abbreviation:

ISSN: 0148-5717

DAY: 3

MONTH: Apr

YEAR: 2007

Rectal microbicide acceptability: results of a volume escalation trial. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7705941

Rectal microbicide acceptability: results of a volume escalation trial. Keywords Mesh Terms:

KEYWORDS: Unsafe Sex

MESH TERMS: prevention & control

Chemical & Substance for Abstract: Rectal microbicide acceptability: results of a volume escalation trial. Information

Substance Name: Gels

Registry Number: 0

Grant and Affiliation Information for Rectal microbicide acceptability: results of a volume escalation trial.

AFFILIATION: HIV Center for Clinical and Behavioral Studies at New York State Psychiatric Institute and Columbia University, New York, NY 10032, and Miriam Hospital/Brown University, Providence, RI, USA. ac72@columbia.edu

Country: United States

AGENCY: United States PHS

GRANT: R01 046060-01

ACRONYM:

MEDLINETA: Sex Transm Dis

REFSOURCE:

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