Recent developments in cell-based immune therapy for neuroblastoma.

Recent developments in cell-based immune therapy for neuroblastoma. Research Abstract Details 

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Recent developments in cell-based immune therapy for neuroblastoma. Abstract Text:

Michael R Verneris,John E Wagner,

Neuroblastoma (NB) is a common and aggressive tumor of early childhood. To date, treatment with chemotherapy, surgery, and radiation therapy has resulted in suboptimal outcomes in those with advanced disease. Immune-based treatments hold promise for patients with recurrent or advanced NB. Here, recent preclinical studies and early stage (phase I) clinical trials using cellular therapeutic approaches for NB are reviewed, including studies of natural killer cells, gammadelta T cells, chimeric receptor expressing T cells, dendritic cells, and allogeneic hematopoietic cell transplant.

Recent developments in cell-based immune therapy for neuroblastoma. Publishing Authors By Initials

MR Verneris,JE Wagner,

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Recent developments in cell-based immune therapy for neuroblastoma. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of neuroimmune pharmacology : the official

VOLUME: 2

Page Numbers: 134-9

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ISSN: 1557-1904

DAY: 2

MONTH: 03

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: Blood and Marrow Transplant Program, Department of Pediatrics, University of Minnesota, Mayo Mail Code 366, 420 Delaware Street, S.E., Minneapolis, MN 55455, USA. verneris@umn.edu

Country: United States

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MEDLINETA: J Neuroimmune Pharmacol

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