Reactive lymphoid hyperplasia of the liver: a case report and review of literature.

Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Research Abstract Details 

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Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Abstract Text:

Takuro Machida,Toshiyuki Takahashi,Tomoo Itoh,Michiaki Hirayama,Takayuki Morita,Shoichi Horita,

A case of a 53-year-old female patient with reactive lymphoid hyperplasia (RLH), clinically designated as pseudolymphoma of the liver is described in this article. The patient was admitted to our hospital for further evaluation of hepatic tumors incidentally discovered at another hospital. Various diagnostic methods, including ultrasonography (US), computerized tomography (CT), magnetic resonance imaging (MRI) and hepatic angiography displayed three small lesions in the liver with outstanding findings consistent with hepatocellular carcinoma (HCC). Surgical resection was performed and the three lesions were microscopically diagnosed as RLH of the liver. The lesions comprised a massive infiltration of lymphoid cells with follicles and hyalinized inter-follicular spaces. Immunohistochemical examination revealed that infiltrating lymphocytes had no prominent nuclear atypia and polyclonality. RLH of the liver is a very rare condition and only twelve cases have been reported in the English literature. Majority of the reported cases were middle-aged women and about half of them had some immunologic abnormalities such as autoimmune thyroiditis, Sjogren's syndrome, primary immunodeficiency, primary biliary cirrhosis. Since they are often clinically misdiagnosed as HCC, surgery is the choice of treatment for these patients. Although their pathology resembles malignant lymphoma, the clinical course is completely benign. The authors propose that RLH of the liver can be discriminated from HCC by its clinical features.

Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Publishing Authors By Initials

T Machida,T Takahashi,T Itoh,M Hirayama,T Morita,S Horita,

For similar hemic and lymphatic diseases: lymphatic diseases: pseudolymphoma research abstracts see: hemic and lymphatic diseases: lymphatic diseases: pseudolymphoma research

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Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Journal Published:

PUBLICATION TYPE: Review

Journal: World journal of gastroenterology : WJG

VOLUME: 13

Page Numbers: 5403-7

Journal Abbreviation: World J. Gastroenterol.

ISSN: 1007-9327

DAY: 28

MONTH: Oct

YEAR: 2007

Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Information

Number of References: 19

LANGUAGE: eng

NlmUniqueID: 100883448

Reactive lymphoid hyperplasia of the liver: a case report and review of literature. Keywords Mesh Terms:

KEYWORDS: Pseudolymphoma

MESH TERMS: pathology

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Grant and Affiliation Information for Reactive lymphoid hyperplasia of the liver: a case report and review of literature.

AFFILIATION: Department of Internal Medicine, Hokkaido Gastroenterology Hospital, Sapporo, Hokkaido 065-0041, Japan.

Country: China

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MEDLINETA: World J Gastroenterol

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