Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen.

Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Research Abstract Details 

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Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Abstract Text:

Timothy E Barder,Stephen L Buchwald,

Electron-rich dialkylbiaryl phosphines, which comprise a common class of supporting ligands for Pd-catalyzed cross-coupling reactions, are highly resistant toward oxidation by molecular oxygen. Presented herein are possible reasons why this class of phosphine ligands manifests this property. Experimental and theoretical data suggest that the two alkyl substituents on the phosphorus center and the 2' and 6' positions of the biaryl backbone play an important role in inhibiting oxidation of this class of ligands.

Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Publishing Authors By Initials

TE Barder,SL Buchwald,

For similar inorganic chemicals: phosphorus compounds: phosphines research abstracts see: inorganic chemicals: phosphorus compounds: phosphines research

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Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of the American Chemical Society

VOLUME: 129

Page Numbers: 5096-101

Journal Abbreviation:

ISSN: 0002-7863

DAY: 28

MONTH: 03

YEAR: 2007

Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Keywords Mesh Terms:

KEYWORDS: Phosphines

MESH TERMS: chemistry

Chemical & Substance for Abstract: Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Information

Substance Name: Oxygen

Registry Number: 7782-44-7

Grant and Affiliation Information for Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen.

AFFILIATION: Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM-46059

ACRONYM: GM

MEDLINETA: J Am Chem Soc

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