Rapidly regulated genes are intron poor.

Rapidly regulated genes are intron poor. Research Abstract Details 

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Rapidly regulated genes are intron poor. Abstract Text:

We show that genes with rapidly changing expression levels in response to stress contain significantly lower intron densities in yeasts, thale cress and mice. Therefore, we propose that introns can delay regulatory responses and are selected against in genes whose transcripts require rapid adjustment for survival of environmental challenges. These findings could provide an explanation for the apparent extensive intron loss during the evolution of some eukaryotic lineages.

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Rapidly regulated genes are intron poor. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Trends in genetics : TIG

VOLUME: 24

Page Numbers: 375-8

Journal Abbreviation: Trends Genet.

ISSN: 0168-9525

DAY: 27

MONTH: 06

YEAR: 2008

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LANGUAGE: eng

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Grant and Affiliation Information for Rapidly regulated genes are intron poor.

AFFILIATION: Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

Country: England

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MEDLINETA: Trends Genet

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