Rapid viral quasispecies evolution: implications for vaccine and drug strategies.

Rapid viral quasispecies evolution: implications for vaccine and drug strategies. Research Abstract Details 

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Rapid viral quasispecies evolution: implications for vaccine and drug strategies. Abstract Text:

I S Novella,E Domingo,J J Holland,I S Novella,E Domingo,J J Holland,

High mutation rates occurring during replication allow RNA viruses to evolve rapidly and adapt continuously to new environments. This poses an enormous challenge to vaccine and drug development which, to be effective, must consider RNA virus variability and follow approaches that minimize the probability of escape or resistant mutants arising.

Rapid viral quasispecies evolution: implications for vaccine and drug strategies. Publishing Authors By Initials

IS Novella,E Domingo,JJ Holland,IS Novella,E Domingo,JJ Holland,

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Rapid viral quasispecies evolution: implications for vaccine and drug strategies. Journal Published:

PUBLICATION TYPE: Review

Journal: Molecular medicine today

VOLUME: 1

Page Numbers: 248-53

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ISSN: 1357-4310

DAY: 4

MONTH: Aug

YEAR: 1995

Rapid viral quasispecies evolution: implications for vaccine and drug strategies. Information

Number of References: 28

LANGUAGE: eng

NlmUniqueID: 9508560

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Grant and Affiliation Information for Rapid viral quasispecies evolution: implications for vaccine and drug strategies.

AFFILIATION: Department of Biology and Institute for Molecular Genetics, University of California, San Diego, La Jolla 92093-0016, USA. isabel@jeeves.ucsd.edu

Country: England

AGENCY: United States NIAID

GRANT: AI14627

ACRONYM: AI

MEDLINETA: Mol Med Today

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