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[Radiotherapy of local recurrence of rectal carcinoma]

[Radiotherapy of local recurrence of rectal carcinoma] Research Abstract Details 

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  • [Radiotherapy of local recurrence of rectal carcinoma] Abstract Text:

    lj radosevi?-jeli?Lj Radosevi?-Jeli?,m durbabaM Durbaba,d s?epanovi?D S?epanovi?,t pekmezovi?T Pekmezovi?,j stankovi?J Stankovi?,

    In retrospective, non-randomized study were analyzed 45 patients with local recurrences of rectal carcinoma treated by combined external beam radiotherapy (EBRT) and "High dose rate (HDR) remote afterloading" brachytherapy in the period from January 1st, 1988 to May 1st, 1988. Depending on the localization of the local recurrent disease, 20 patients were with vaginal relapse, 13 with vaginal and presacral, 9 with perineal and 3 with presacral and rectal. Combined radiotherapy was applied as follows: 33 patients (73.3%) had EBRT with endovaginal brachytherapy, 3 (6.7%) EBRT plus intraluminal brachytherapy and 9 (20%) patients EBRT plus interstitial brachytherapy. Techniques with 3 and 4 field for EBRT were used and doses ranged 45-65 Gy with convenient fractionation were applied, combined with the doses ranged 15-35 Gy for brachytherapy. Radiotherapy was planned according to the computer tomography cross image on simulator with computer planning. Complete regression of the tumor was observed in 19 patients (42.2%), and partial in 23 patients (51.1%). Median follow-up period was 34 months (8-72). Acute radiation adverse effects were registered in 32 patients, and late sequels in 6 (13.3%). Overall 3-year survival rate was 54% and disease-free survival rate was 34% in the same period.

    [Radiotherapy of local recurrence of rectal carcinoma] Publishing Authors By Initials

    lj radosevi?-jeli?Lj Radosevi?-Jeli?,m durbabaM Durbaba,d s?epanovi?D S?epanovi?,t pekmezovi?T Pekmezovi?,j stankovi?J Stankovi?,

    For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research

    PUBMED ID PMID:

    MEDLINE DATE: 1998 Nov-Dec

    [Radiotherapy of local recurrence of rectal carcinoma] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Vojnosanitetski pregled. Military-medical and phar

    VOLUME: 55

    Page Numbers: 595-9

    Journal Abbreviation:

    ISSN: 0042-8450

    DAY: 9

    MONTH: 01

    YEAR: 2008

    [Radiotherapy of local recurrence of rectal carcinoma] Information

    Number of References:

    LANGUAGE: scc

    NlmUniqueID: 21530700

    [Radiotherapy of local recurrence of rectal carcinoma] Keywords Mesh Terms:

    KEYWORDS: Retrospective Studies

    MESH TERMS: radiotherapy

    Chemical & Substance for Abstract: [Radiotherapy of local recurrence of rectal carcinoma] Information

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    Grant and Affiliation Information for [Radiotherapy of local recurrence of rectal carcinoma]

    AFFILIATION:

    Country: YUGOSLAVIA

    YUGOSLAVIA Research PublicationYUGOSLAVIA Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Vojnosanit Pregl

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