Radiotherapy for head and neck cancer: latest developments and future perspectives.

Radiotherapy for head and neck cancer: latest developments and future perspectives. Research Abstract Details 

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Radiotherapy for head and neck cancer: latest developments and future perspectives. Abstract Text:

Jacques Bernier,Soeren M Bentzen,Jacques Bernier,Soeren M Bentzen,Jacques Bernier,Soeren M Bentzen,

PURPOSE OF REVIEW: Despite recent advances in multimodality management the prognosis of patients with stage III-IV squamous cell head and neck cancer remains disappointing. The objective of this review is to identify how, within the main axes of the current translational and clinical research and in an attempt to improve treatment outcome, a number of institutions and cooperative groups have embarked on systematic investigations of novel strategies for radiotherapy delivery and for combining radiation with systemic treatments. RECENT FINDINGS: Four domains of translational and clinical researches can be identified in head and neck radio-oncology: altered fractionation, concurrent delivery of chemotherapy and radiotherapy, combination of targeted therapies with radiation, and high-conformality radiotherapy. SUMMARY: Here we provide a critical appraisal of recent strategies allowing an increase in dose intensity for treatments based on radiotherapy and drug-radiation interactions, and revisit the potential opportunities they offer as well as the possible caveats they may present in patients with locally advanced head and neck cancers.

Radiotherapy for head and neck cancer: latest developments and future perspectives. Publishing Authors By Initials

J Bernier,SM Bentzen,J Bernier,SM Bentzen,J Bernier,SM Bentzen,

For similar therapeutics: radiotherapy: radiotherapy, computer-assisted: radiotherapy, conformal: radiotherapy, intensity-modulated research abstracts see: therapeutics: radiotherapy: radiotherapy, computer-assisted: radiotherapy, conformal: radiotherapy, intensity-modulated research

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Radiotherapy for head and neck cancer: latest developments and future perspectives. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in oncology

VOLUME: 18

Page Numbers: 240-6

Journal Abbreviation:

ISSN: 1531-703X

DAY: 20

MONTH: May

YEAR: 2006

Radiotherapy for head and neck cancer: latest developments and future perspectives. Information

Number of References: 64

LANGUAGE: eng

NlmUniqueID: 9007265

Radiotherapy for head and neck cancer: latest developments and future perspectives. Keywords Mesh Terms:

KEYWORDS: Radiotherapy, Intensity-Modulated

MESH TERMS: trends

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Grant and Affiliation Information for Radiotherapy for head and neck cancer: latest developments and future perspectives.

AFFILIATION: Department of Radio-Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland. Jacques.bernier@hcuge.ch

Country: United States

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MEDLINETA: Curr Opin Oncol

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