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Race, ethnicity, and use of thiazolidinediones among US adults with diabetes.

Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Research Abstract Details 

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  • Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Abstract Text:

    christina l aquilanteChristina L Aquilante,weiming zhangWeiming Zhang,marianne mccollumMarianne McCollum,

    OBJECTIVE: Significant race and ethnic disparities exist in diabetes-related health care. Using a nationally representative database, we sought to determine if use of thiazolidinediones (TZDs) differs by race and ethnicity. As a secondary objective, we sought to determine if race and ethnicity is associated with use of older oral antidiabetic agents, such as sulfonylureas and metformin. RESEARCH DESIGN AND METHODS: Adult respondents to the 2003 Medical Expenditure Panel Survey with diabetes, identified by diagnosis code or self-report, were included. Race/ethnic groups were defined as: White/not-Hispanic; Black/not-Hispanic; Hispanic; or Other/not-Hispanic. Associations between use of oral antidiabetic agents (defined as > or = 1 prescription for a TZD, sulfonylurea, or metformin) and race/ethnicity, sex, age, insurance status, poverty status, and having a usual source of care were evaluated in univariate analyses with chi(2) tests and in adjusted analyses using logistic regression methods for survey data. RESULTS: A total of 1873 US adults with diabetes were identified, with use of oral antidiabetic agents varying by drug class: 23.1% received TZDs, 45.3% received metformin, and 43.8% received sulfonylureas. Use of oral antidiabetic agents, by drug class, did not differ significantly by race/ethnicity (p = 0.33 for TZDs, p = 0.43 for metformin, p = 0.38 for sulfonylureas). In univariate analyses, only insurance status was significantly associated with use of TZDs (p = 0.03), and no variables were associated with use of sulfonylureas or metformin. In adjusted logistic regression analyses, there were no significant predictors of the use of TZDs or metformin, and only age was significantly associated with the use of sulfonylureas. CONCLUSIONS: In a nationally representative database, fewer US adults with diabetes received TZDs compared with sulfonylureas or metformin in 2003. Although we were not able to differentiate between type 1 and type 2 diabetes, nor did we assess oral agent monotherapy versus combination therapy, we found that use of TZDs, sulfonylureas, and metformin did not differ based on race/ethnicity or other demographic variables such as sex, insurance status, poverty status, or having a usual source of health care.

    Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Publishing Authors By Initials

    cl aquilanteCL Aquilante,w zhangW Zhang,m mccollumM McCollum,

    For similar geographic locations: americas: north america: united states research abstracts see: geographic locations: americas: north america: united states research

    PUBMED ID PMID:

    MEDLINE DATE:

    Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Journal Published:

    PUBLICATION TYPE: Research Support, N.I.H., Extr

    Journal: Current medical research and opinion

    VOLUME: 23

    Page Numbers: 489-94

    Journal Abbreviation:

    ISSN: 1473-4877

    DAY: 3

    MONTH: Mar

    YEAR: 2007

    Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 351014

    Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Keywords Mesh Terms:

    KEYWORDS: United States

    MESH TERMS: economics

    Chemical & Substance for Abstract: Race, ethnicity, and use of thiazolidinediones among US adults with diabetes. Information

    Substance Name: Metformin

    Registry Number: 657-24-9

    Grant and Affiliation Information for Race, ethnicity, and use of thiazolidinediones among US adults with diabetes.

    AFFILIATION: School of Pharmacy, Department of Pharmaceutical Sciences, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA.

    Country: England

    England Research PublicationEngland Research Publication

    AGENCY: United States NIDDK

    GRANT: K23 DK073197

    ACRONYM: DK

    MEDLINETA: Curr Med Res Opin

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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