Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development.

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Abstract Text:

David R Natale,Andrew J Watson,

Adherens junction formation is fundamental for compaction and trophectoderm differentiation during mammalian preimplantation development. We recently isolated an IQGAP-2 cDNA from a differential display-polymerase chain reaction screen of bovine preimplantation developmental stages. IQGAP-1 and -2 proteins mediate E-cadherin-based cell-to-cell adhesion through interactions with beta-catenin and the Rho GTPases, rac1 and cdc42. Our study demonstrates IQGAP-1,-2, rac-1 and cdc42 mRNAs are present throughout murine preimplantation development. IQGAP-1 and rac-1 protein distribution changes from predominantly plasma membrane associated to predominantly cytoplasmic as the embryo progresses through cleavage divisions and compaction to the blastocyst stage.

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Publishing Authors By Initials

DR Natale,AJ Watson,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Mechanisms of development

VOLUME: 119 Suppl 1

Page Numbers: S21-6

Journal Abbreviation: Mech. Dev.

ISSN: 0925-4773

DAY: 30

MONTH: Dec

YEAR: 2002

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9101218

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development.

AFFILIATION: Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada N6A 5C1.

Country: Ireland

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Mech Dev

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development Related Publications

• A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment.
• Advancing quality of urinary incontinence evaluation and treatment in nursing homes through translational research.
• Assessing acrosomal status of bovine sperm using fluoresceinated lectins.
• Characterization of epithelial cell shedding from human small intestine.
• Clinical report: Recovery of a degenerating 14-day embryo in the uterine flush of a mare 7 days after ovulation.
• Current status of newborn screening: decision-making about the conditions to include in screening programs.
• Distraction osteogenesis.
• Do mares possess an intracellular endometrial inhibitor of prostaglandin synthesis during early pregnancy?
• Effect of bone morphogenetic proteins 2 and 7 on septal chondrocytes in alginate.
• Health seeking behavior by families of children suspected to have malaria in Kabale: Uganda.
• Histiocytic sarcoma of the spleen in flat-coated retrievers with regenerative anaemia and hypoproteinaemia.
• Hp19 re-operation for Dysphagia after cardiomyotomy for achalasia.
• Hp23 use of anti-reflux medication after anti-reflux surgery.
• Hp33p laparoscopic anti-reflux surgery in the elderly.
• Human Papillomavirus: Confronting the Epidemic-A Urologist's Perspective.
• Lowering levels of lipids and homocysteine.
• Molecular mechanisms of megakaryopoiesis.
• Paradoxical embolism secondary to ovarian carcinoma resulting in stroke.
• Prostate-derived ETS factor is a mediator of metastatic potential through the inhibition of migration and invasion in breast cancer.
• Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development.
• Screening for colorectal cancer using the faecal occult blood test, Hemoccult.
• Single- versus dual-process models of lexical decision performance: insights from response time distributional analysis.
• Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy.
• Stroke prevention in atrial fibrillation: antiplatelet therapy revisited.
• The effect of buffer osmolality on the survival of cat (Felis catus ) spermatozoa at 5 degrees C.
• The effect of high and low dose Theileria parva infection on the reproductive function of Boran/Friesian heifers.
• The effect of transcervical uterine manipulations on establishment of uterine infection in mares under the influence of progesterone.
• The effects of low level of feeding on response to synchronization of estrus, ovulation rate and embryo loss in goats.
• Understanding the impact of stigma on people with mental illness.
• von Willebrand factor mediates platelet spreading through glycoprotein Ib and alpha(IIb)beta3 in the presence of botrocetin and ristocetin, respectively.