"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila.

"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Research Abstract Details 

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"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Abstract Text:

M F Wolfner,

The seminal fluid that females receive from their mates contains a suite of proteins that have important effects on sperm, as well as on reproduction in general. Seminal proteins are vital for the fertility of mating animals in several diverse taxonomic groups. For example, in Drosophila melanogaster, the approximately 70-106 accessory gland proteins (Acps) that are a major part of the seminal fluid are essential for the storage and utilization of sperm, as well as for increasing egg production and laying by the female. In addition, Acps have been implicated in modifying the female's eating behaviour, her receptivity to re-mating and her longevity. This review will first summarise the molecular nature and reproductive function of Drosophila Acps in general, as elucidated by genetic/ transgenesis, biochemical, and physiological experiments. The article will then focus on Acps that affect, or interact with, sperm. Sperm storage is a stepwise process in Drosophila and Acps facilitate at least some of these steps. For example, Acps promote sperm entry into storage, apparently by modulating muscle contractions in the female's reproductive tract. One Acp is known to be essential for the entry of sperm into storage. This Acp, which is cleaved after entering females, binds to sperm and enters the sperm-storage organs. Egg production, which is also modulated by Acps, can affect the transition between the steps in sperm storage, although not the rate of release of sperm from storage. Results on additional roles of Acp-sperm interaction in Drosophila will be reviewed.

"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Publishing Authors By Initials

MF Wolfner,

For similar proteins: seminal plasma proteins research abstracts see: proteins: seminal plasma proteins research

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"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Journal Published:

PUBLICATION TYPE: Review

Journal: Society of Reproduction and Fertility supplement

VOLUME: 65

Page Numbers: 183-99

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DAY: 19

MONTH: 11

YEAR: 2007

"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Information

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LANGUAGE: eng

NlmUniqueID: 101295315

"S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Keywords Mesh Terms:

KEYWORDS: Seminal Plasma Proteins

MESH TERMS: physiology

Chemical & Substance for Abstract: "S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila. Information

Substance Name: male accessory gland peptide, Drosophila

Registry Number: 0

Grant and Affiliation Information for "S.P.E.R.M." (seminal proteins (are) essential reproductive modulators): the view from Drosophila.

AFFILIATION: Department of Molecular Biology and Genetics, Cornell University, Ithaca NY 14853, USA. mfw5@cornell.edu

Country: England

AGENCY: United States NICHD

GRANT: HD38921

ACRONYM: HD

MEDLINETA: Soc Reprod Fertil Suppl

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