Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging.

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Abstract Text:

Theodore J Huppert,Rick D Hoge,Anders M Dale,Maria A Franceschini,David A Boas,

Akin to functional magnetic resonance imaging (fMRI), diffuse optical imaging (DOI) is a noninvasive method for measuring localized changes in hemoglobin levels within the brain. When combined with fMRI methods, multimodality approaches could offer an integrated perspective on the biophysics, anatomy, and physiology underlying each of the imaging modalities. Vital to the correct interpretation of such studies, control experiments to test the consistency of both modalities must be performed. Here, we compare DOI with blood oxygen level-dependent (BOLD) and arterial spin labeling fMRI-based methods in order to explore the spatial agreement of the response amplitudes recorded by these two methods. Rather than creating optical images by regularized, tomographic reconstructions, we project the fMRI image into optical measurement space using the optical forward problem. We report statistically better spatial correlation between the fMRI-BOLD response and the optically measured deoxyhemoglobin (R=0.71, p=1x10(-7)) than between the BOLD and oxyhemoglobin or total hemoglobin measures (R=0.38, p=0.04|0.37, p=0.05, respectively). Similarly, we find that the correlation between the ASL measured blood flow and optically measured total and oxyhemoglobin is stronger (R=0.73, p=5x10(-6) and R=0.71, p=9x10(-6), respectively) than the flow to deoxyhemoglobin spatial correlation (R=0.26, p=0.10).

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Publishing Authors By Initials

TJ Huppert,RD Hoge,AM Dale,MA Franceschini,DA Boas,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: tomography: tomography, optical research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: tomography: tomography, optical research

PUBMED ID PMID:

MEDLINE DATE: 2006 Nov-Dec

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biomedical optics

VOLUME: 11

Page Numbers: 064018

Journal Abbreviation:

ISSN: 1083-3668

DAY: 3

MONTH: 12

YEAR: 2007

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9605853

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Keywords Mesh Terms:

KEYWORDS: Tomography, Optical

MESH TERMS: methods

Chemical & Substance for Abstract: Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. Information

Substance Name: Oxygen

Registry Number: 7782-44-7

Grant and Affiliation Information for Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging.

AFFILIATION: Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA. thuppert@nmr.mgh.harvard.edu

Country: United States

AGENCY: United States NIBIB

GRANT: R01-EB002482

ACRONYM: EB

MEDLINETA: J Biomed Opt

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging Related Publications

• 280.
• A multicompartment vascular model for inferring baseline and functional changes in cerebral oxygen metabolism and arterial dilation.
• A time domain fluorescence tomography system for small animal imaging.
• Assessing infants' cortical response to speech using near-infrared spectroscopy.
• Boyle as a theoretical scientist.
• Comparison of frequency-domain and time-domain fluorescence lifetime tomography.
• Compression-induced changes in the physiological state of the breast as observed through frequency domain photon migration measurements.
• Coupling between somatosensory evoked potentials and hemodynamic response in the rat.
• Dendrimer based anti-infective and anti-inflammatory drugs.
• Depth-resolved imaging of functional activation in the rat cerebral cortex using optical coherence tomography.
• Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation.
• Diffuse optical imaging of the whole head.
• Distinctive features of coronary disease in the aged.
• Dynamic functional and mechanical response of breast tissue to compression.
• Estimation and statistical bounds for three-dimensional polar shapes in diffuse optical tomography.
• Genetics of atherosclerosis; studies of families with xanthoma and unselected patients with coronary artery disease under the age of 50 years.
• Hemodynamic response to featural changes in the occipital and inferior temporal cortex in infants: a preliminary methodological exploration.
• Intraspinal administration of penicillin in general paralysis.
• Lipoatrophy following the injection of insulin; a method of control.
• Optical imaging of phonological processing in two distinct orthographies.
• Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging.
• The evolution of calcareous aortic stenosis.
• The need for a national health program.
• Time-gated optical system for depth-resolved functional brain imaging.
• Transport-based image reconstruction in turbid media with small source-detector separations.
• [Not Available.]
• [Not Available.]
• [Observations on value of Medicinal Praecutans in skin diseases.]
• [Statistics on venereal disease in Denmark during and following each of the two world wars.]
• [Treatment of scabies with novoscabin.]