[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay]

[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay] Research Abstract Details 

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[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay] Abstract Text:

Q Jian,Y Xie,H Xie,

OBJECTIVE: In order to investigate whether cord blood transplantation could induce severe graft versus host disease (GVHD) similar to that in bone marrow transplantation. METHODS: The frequency of allospecific IL-2-secreting helper T lymphocyte (AIHTL) in 17 cord blood and 14 adult peripherial blood samples were detected by limiting dilution assay. RESULTS: No statistically significant difference between the cord blood and adult peripheral blood AIHTLs was revealed. CONCLUSION: Alloreactivity of cord blood was the same as that of adult blood. HLA typing and powerful immunosuppressive therapy should be adopted to reduce the incidence of GVHD in cord blood transplantation.

[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay] Publishing Authors By Initials

Q Jian,Y Xie,H Xie,

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[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zaz

VOLUME: 18

Page Numbers: 588-91

Journal Abbreviation: Zhonghua Xue Ye Xue Za Zhi

ISSN: 0253-2727

DAY: 31

MONTH: Nov

YEAR: 1997

[Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay] Information

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LANGUAGE: chi

NlmUniqueID: 8212398

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Grant and Affiliation Information for [Quantitative assessment of allospecific interleukin-2-secreting helper T lymphocyte in cord blood with limiting dilution assay]

AFFILIATION: Huashan Hospital, Shanghai Medical University, Shanghai 200040.

Country: China

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MEDLINETA: Zhonghua Xue Ye Xue Za Zhi

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