Quality assessment and microbiologic screening of donor corneas.

Quality assessment and microbiologic screening of donor corneas. Research Abstract Details 

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Quality assessment and microbiologic screening of donor corneas. Abstract Text:

Sohela S Hassan,Kirk R Wilhelmus,Sohela S Hassan,Kirk R Wilhelmus,

PURPOSE: To identify possible predictors of donor corneal contamination. METHODS: Relationships between eye-banking characteristics of donor corneas and surgical corneoscleral rim culture results were examined in a retrospective case-control study by using logistic regression to estimate odds ratios (ORs) with 95% confidence intervals (CIs). RESULTS: Of 263 donor corneal rims, microbial recovery occurred from 23 (9%), including 6 yielding Clostridium perfringens. After adjusting for outdoor temperature and death-to-preservation duration, a positive rim culture occurred more often among tissues having an acceptable but less favorable biomicroscopic rating (OR, 4.22; 95% CI, 1.27-13.98). CONCLUSIONS: This exploratory study suggests that slit-lamp assessment of corneal appearance may correlate with subsequent microbiologic results. Ensuring optimal selection and preservation of the donor cornea may contribute to the safety of eye banking.

Quality assessment and microbiologic screening of donor corneas. Publishing Authors By Initials

SS Hassan,KR Wilhelmus,SS Hassan,KR Wilhelmus,

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Quality assessment and microbiologic screening of donor corneas. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Cornea

VOLUME: 26

Page Numbers: 953-5

Journal Abbreviation: Cornea

ISSN: 0277-3740

DAY: 27

MONTH: Sep

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 8216186

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Grant and Affiliation Information for Quality assessment and microbiologic screening of donor corneas.

AFFILIATION: Lions Eye Bank of Texas at Baylor College of Medicine, and the Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.

Country: United States

AGENCY: United States NEI

GRANT: EY016631

ACRONYM: EY

MEDLINETA: Cornea

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