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Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives.

Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Research Abstract Details 

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  • Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Abstract Text:

    Within the scope of a study of antitumour compounds in higher plants a survey is given concerning the presence of pyrrolizidine alkaloids, flavonoids and volatile compounds in Eupatorium species. Preliminary results of a phytochemical study of these compounds in E. cannabinum are also presented. From the results of a GC-MS analysis of an alkaloid extract from aerial parts of E. cannabinum the conclusion can be drawn, that the composition of pyrrolizidine alkaloids is more complicated than reported in literature. This is caused by the fact that different stereoisomers exist. The presence of at least two alkaloids with a molecular weight of 283 (supinine or isomers) and four alkaloids with a molecular weight of 299 (echinatine or isomers) could be shown. In subterranean plant material also other pyrrolizidine alkaloids are present. A great number of flavonoids, also as glycosides, have been shown in Eupatorium species, often in low quantities. Rutin, present in many Eupatorium species, could not be detected in subterranean parts of E. cannabinum. Relatively little attention has been paid to the analysis of volatile compounds (essential oils) of Eupatorium species. Thymol derivatives are often reported to be present in Eupatorium species. Thirty-five compounds could be detected by means of a GC-MS analysis in the essential oil of E. cannabinum about which no literature data were available.

    Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Publishing Authors By Initials

    For similar heterocyclic compounds: alkaloids: pyrrolizidine alkaloids research abstracts see: heterocyclic compounds: alkaloids: pyrrolizidine alkaloids research

    PUBMED ID PMID:

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    Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Pharmaceutisch weekblad. Scientific edition

    VOLUME: 5

    Page Numbers: 281-6

    Journal Abbreviation:

    ISSN: 0167-6555

    DAY: 16

    MONTH: Dec

    YEAR: 1983

    Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Information

    Number of References: 35

    LANGUAGE: eng

    NlmUniqueID: 7907992

    Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Keywords Mesh Terms:

    KEYWORDS: Pyrrolizidine Alkaloids

    MESH TERMS: analysis

    Chemical & Substance for Abstract: Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives. Information

    Substance Name: Pyrrolizidine Alkaloids

    Registry Number: 0

    Grant and Affiliation Information for Pyrrolizidine alkaloids, flavonoids and volatile compounds in the genus Eupatorium. Eupatorium cannabinum L., an ancient drug with new perspectives.

    AFFILIATION:

    Country: NETHERLANDS

    NETHERLANDS Research PublicationNETHERLANDS Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Pharm Weekbl Sci

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    Number Hits: 0

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