Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps.

Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps. Research Abstract Details 

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Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps. Abstract Text:

H Yamada,K Ohtani,H Kiyohara,J C Cyong,Y Otsuka,Y Ueno,S Omura,

The polysaccharide fraction from the leaves of ARTEMISIA PRINCEPS Pamp (Japanese name = Gaiy?) showed a potent anti-complementary activity. Two major active polysaccharides (AAF-IIb-2 and IIb-3) were purified by ion exchange chromatography on DEAE-Sepharose, affinity chromatography on RICINUS COMMUNIS-agglutinin conjugated Sepharose and gel filtration on Sephadex G-100 and Sepharose CL-4B. The molecular weights of AAF-IIb-2 and IIb-3 were found to be 139 000 and 31 000 by the calibration of gel filtration. AAF-IIb-2 and IIb-3 were composed by rhamnose, xylose, arabinose, galactose and glucose in the molar ratios of 2.5:2.5:4.3:3.6:1.0 and 1.5:1.0:9.4:7.5:1.0, and also contained 59.4% and 49.0% galacturonic acid, respectively. AAF-IIb-2 was shown to have the more potent activity than AAF-IIb-3. Anti-complementary activity of AAF-IIb-3 was almost similar with that of crude AR-arabinogalactan from the root of ANGELICA ACUTILOBA Kitagawa, but AAF-IIb-2 and IIb-3 showed more potent activity than anti-complementary beta-glucan, lentinan.

Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps. Publishing Authors By Initials

H Yamada,K Ohtani,H Kiyohara,JC Cyong,Y Otsuka,Y Ueno,S Omura,

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Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Planta medica

VOLUME: 51

Page Numbers: 121-5

Journal Abbreviation: Planta Med.

ISSN: 0032-0943

DAY: 6

MONTH: Apr

YEAR: 1985

Purification and Chemical Properties of Anti-complementary Polysaccharide from the Leaves of Artemisia princeps. Information

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LANGUAGE: eng

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AFFILIATION: Oriental Medicine Research Center of the Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108, Japan.

Country: Germany

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MEDLINETA: Planta Med

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