Pulmonary surfactant and chronic lung disease.

Pulmonary surfactant and chronic lung disease. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Pulmonary surfactant and chronic lung disease. Abstract Text:

T Higenbottam,

Chronic obstructive bronchitis and emphysema are two chronic lung diseases closely associated with cigarette smoking. Early pathological changes in the lung in asymptomatic smokers affect the alveoli and bronchioli, sites where surfactant production is centred. Bronchial lavage work has demonstrated a reduction of 'free' extra-cellular surfactant in smokers. In this report the interaction between the 'tar' of tobacco smoke and surfactant is described from in vitro studies. Also using an isolated rat lung model tobacco smoke 'tar' appears to increase lung compliance. These observations may help explain why young asymptomatic cigarette smokers have increased lung compliance and suggest the way in which 'tar' interacts with the lung surface.

Pulmonary surfactant and chronic lung disease. Publishing Authors By Initials

T Higenbottam,

For similar behavior and behavior mechanisms: behavior: habits: smoking research abstracts see: behavior and behavior mechanisms: behavior: habits: smoking research

PUBMED ID PMID:

MEDLINE DATE:

Pulmonary surfactant and chronic lung disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of respiratory diseases. Suppleme

VOLUME: 153

Page Numbers: 222-8

Journal Abbreviation:

ISSN: 0106-4347

DAY: 21

MONTH: 02

YEAR: 1987

Pulmonary surfactant and chronic lung disease. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8010618

Pulmonary surfactant and chronic lung disease. Keywords Mesh Terms:

KEYWORDS: Smoking

MESH TERMS: adverse effects

Chemical & Substance for Abstract: Pulmonary surfactant and chronic lung disease. Information

Substance Name: Pulmonary Surfactants

Registry Number: 0

Grant and Affiliation Information for Pulmonary surfactant and chronic lung disease.

AFFILIATION: Department of Respiratory Physiology, Papworth Hospital, Cambridge, England.

Country: DENMARK

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Eur J Respir Dis Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Pulmonary surfactant and chronic lung disease Related Publications

• Acute and chronic rejection of the lung following heart and lung transplantation.
• Exacerbation-Free COPD: A Goal Too Far?
• Pulmonary surfactant and chronic lung disease.
• Quantifying of severity of exacerbations in chronic obstructive pulmonary disease: adaptations to the definition to allow quantification.