Pulmonary manifestations of juvenile laryngotracheal papillomatosis.

Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Research Abstract Details 

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Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Abstract Text:

S S Kramer,W D Wehunt,J T Stocker,H Kashima,

Juvenile laryngotracheal papillomatosis spreads to involve the lungs in less than 1% of cases, and when this occurs, the prognosis is poor. In seven such cases, the lung lesions, which appeared either solid or cystic on radiographs, proved to be benign squamous cell proliferations or papillomas, with central cavities containing debris or air. They seemed to grow centrifugally, using the alveolar walls as scaffolding with central coalescence and lung destruction. Papillomas spread inferiorly from the larynx by direct extension as far as the major bronchi, but rarely beyond. However, the parenchymal lesions were widely scattered, and some were subpleural. This discrepancy suggests that fragments become detached, particularly during endoscopic resection, and are carried down the airways by airflow. Those that lodge proximal to the respiratory bronchioles may be removed by mucociliary action and cough. Those that travel more distally are poorly cleared and may grow. If enough lung parenchyma is destroyed, the patient can develop symptoms of restrictive lung disease in addition to signs of upper airway obstruction.

Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Publishing Authors By Initials

SS Kramer,WD Wehunt,JT Stocker,H Kashima,

For similar respiratory tract diseases research abstracts see: respiratory tract diseases research

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Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 144

Page Numbers: 687-94

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ISSN: 0361-803X

DAY: 15

MONTH: Apr

YEAR: 1985

Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Pulmonary manifestations of juvenile laryngotracheal papillomatosis. Keywords Mesh Terms:

KEYWORDS: Respiratory Tract Diseases

MESH TERMS: radiography

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Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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