Psychotropic activity of the antialcohol preparation proproten-100.

Psychotropic activity of the antialcohol preparation proproten-100. Research Abstract Details 

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Psychotropic activity of the antialcohol preparation proproten-100. Abstract Text:

E N Krylov,

Antidepressant Activity of Proproten-100 (antibodies to brain-specific S100 protein in ultralow doses) in patients with stage II alcohol dependence and alcohol withdrawal syndrome was studied in an open comparative clinical trial. The tricyclic antidepressant amitriptyline and benzodiazepine tranquilizer phenazepam served as reference preparations. Anxiolytic activity of Proproten-100 was highly competitive with that of phenazepam. Proproten-100 produced a stronger thymoleptic effect than amitriptyline. The preparation possessed activating properties, affected alcohol addiction, and did not cause side effects. Proproten-100 should undergo clinical tests during the therapy of neurotic, neurosis-like, and subdepressive borderline disorders.

Psychotropic activity of the antialcohol preparation proproten-100. Publishing Authors By Initials

EN Krylov,

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Psychotropic activity of the antialcohol preparation proproten-100. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Bulletin of experimental biology and medicine

VOLUME: 135 Suppl 1

Page Numbers: 176-80

Journal Abbreviation: Bull. Exp. Biol. Med.

ISSN: 0007-4888

DAY: 1

MONTH: 09

YEAR: 2003

Psychotropic activity of the antialcohol preparation proproten-100. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Psychotropic activity of the antialcohol preparation proproten-100.

AFFILIATION: Moscow Institute of Psychiatry, Russian Ministry of Health.

Country: United States

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MEDLINETA: Bull Exp Biol Med

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