The manifestations of mitochondrial disease are variable, affecting more frequently the organs with high aerobic metabolism in which they are more abundant, for example the nervous system. The beginning of symptoms in general is observed at childhood, but some patients presented on adult age. We present an atypical case associated with mitochondrial DNA deletion. A 39-years-old man with psychiatric symptoms that configured initial clinical picture and only after 12 years of the beginning of symptoms neurological alterations became noticeable. The diagnosis of mitochondrial illness was confirmed by muscle biopsy being documented mitochondrial DNA deletion.
[Psychotic syndrome developing into dementia as a clinical manifestation of mitochondrial DNA deletion] Publishing Authors By Initials
[Psychotic syndrome developing into dementia as a clinical manifestation of mitochondrial DNA deletion] Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Arquivos de neuro-psiquiatria
VOLUME: 65
Page Numbers: 114-7
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ISSN: 0004-282X
DAY: 10
MONTH: Mar
YEAR: 2007
[Psychotic syndrome developing into dementia as a clinical manifestation of mitochondrial DNA deletion] Information
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LANGUAGE: por
NlmUniqueID: 125444
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AFFILIATION: Instituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Rua conde de Bonfim 211/702, CEP 20520-050 Rio de Janeiro, RJ, Brazil. luizneurol@terra.com.br
Country: Brazil
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MEDLINETA: Arq Neuropsiquiatr
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