Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation.

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Research Abstract Details 

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Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Abstract Text:

John E Karro,Yangpan Yan,Deyou Zheng,Zhaolei Zhang,Nicholas Carriero,Philip Cayting,Paul Harrrison,Mark Gerstein,

The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current 'consensus' set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (accounting for changing genome builds) and an underlying object-oriented interface designed for researchers with a minimal knowledge of programming. At the present time, the database contains more than 100,000 pseudogenes spanning 64 prokaryote and 11 eukaryote genomes, including a collection of human annotations compiled from 16 sources.

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Publishing Authors By Initials

JE Karro,Y Yan,D Zheng,Z Zhang,N Carriero,P Cayting,P Harrrison,M Gerstein,

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Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Nucleic acids research

VOLUME: 35

Page Numbers: D55-60

Journal Abbreviation: Nucleic Acids Res.

ISSN: 1362-4962

DAY: 11

MONTH: 11

YEAR: 2006

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Information

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LANGUAGE: eng

NlmUniqueID: 411011

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Keywords Mesh Terms:

KEYWORDS: User-Computer Interface

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Grant and Affiliation Information for Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation.

AFFILIATION: Center for Comparative Genomics and Bioinformatics, 506B Wartik, Pennsylvania State University, University Park, PA 16802, USA. jkarro@acm.org

Country: England

AGENCY: United States NHGRI

GRANT: P50 HG02357-01

ACRONYM: HG

MEDLINETA: Nucleic Acids Res

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