PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity.

PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Research Abstract Details 

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PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Abstract Text:

Alison C Badrick,Amanda J Hamilton,Paul V Bernhardt,Christopher E Jones,Ulrike Kappler,Michael P Jennings,Alastair G McEwan,

PrrC is a Sco homologue in Rhodobacter sphaeroides that is associated with PrrBA, a two-component signal transduction system that induces photosynthesis gene expression in response to a decrease in oxygen tension. Although Sco proteins have been shown to bind copper the observation that they are structurally-related to thioredoxins suggested that they might possess thiol-disulfide oxidoreductase activity. Our results show that PrrC reduces Cu(2+) to Cu(+) and possesses disulfide reductase activity. These results indicate that some bacterial Sco proteins may have biochemical properties that are distinct from those of mitochondrial Sco proteins.

PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Publishing Authors By Initials

AC Badrick,AJ Hamilton,PV Bernhardt,CE Jones,U Kappler,MP Jennings,AG McEwan,

For similar proteins: thioredoxins research abstracts see: proteins: thioredoxins research

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PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: FEBS letters

VOLUME: 581

Page Numbers: 4663-7

Journal Abbreviation: FEBS Lett.

ISSN: 0014-5793

DAY: 4

MONTH: 09

YEAR: 2007

PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Information

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LANGUAGE: eng

NlmUniqueID: 155157

PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Keywords Mesh Terms:

KEYWORDS: Thioredoxins

MESH TERMS: metabolism

Chemical & Substance for Abstract: PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. Information

Substance Name: Protein Disulfide Reductase (Glutathione

Registry Number: EC 1.8.4.2

Grant and Affiliation Information for PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity.

AFFILIATION: Centre for Metals in Biology, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia.

Country: Netherlands

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MEDLINETA: FEBS Lett

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