Proteomics analysis in lung cancer: challenges and opportunities.

Proteomics analysis in lung cancer: challenges and opportunities. Research Abstract Details 

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Proteomics analysis in lung cancer: challenges and opportunities. Abstract Text:

Takefumi Kikuchi,David P Carbone,

Recent technological developments in proteomic analysis are bringing us new insights into the molecular classification of tumours. Although proteomic analysis in cancer profiling is still under development both in terms of the instruments used and the data analytical tools, this method has great potential advantages for the analysis of biospecimens of many types. Direct measurement of abnormally expressed or modified proteins in the tumour tissue and/or patient blood may be an effective approach for discovering new biomarkers. Proteomics has the significant advantage of being able to discern not only changes in expression levels but also in post-translational modifications. Thus, the proteomics approach to protein profiling and biomarker discovery uncovers biomarkers from a different viewpoint than microarray analysis. This review summarizes the range of proteomics technologies employed for cancer profiling, and how they have been used to derive new classification models for human lung cancer.

Proteomics analysis in lung cancer: challenges and opportunities. Publishing Authors By Initials

T Kikuchi,DP Carbone,

For similar biological factors: biological markers: tumor markers, biological research abstracts see: biological factors: biological markers: tumor markers, biological research

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Proteomics analysis in lung cancer: challenges and opportunities. Journal Published:

PUBLICATION TYPE: Review

Journal: Respirology (Carlton, Vic.)

VOLUME: 12

Page Numbers: 22-8

Journal Abbreviation: Respirology

ISSN: 1323-7799

DAY: 3

MONTH: Jan

YEAR: 2007

Proteomics analysis in lung cancer: challenges and opportunities. Information

Number of References: 45

LANGUAGE: eng

NlmUniqueID: 9616368

Proteomics analysis in lung cancer: challenges and opportunities. Keywords Mesh Terms:

KEYWORDS: Tumor Markers, Biological

MESH TERMS: analysis

Chemical & Substance for Abstract: Proteomics analysis in lung cancer: challenges and opportunities. Information

Substance Name: Tumor Markers, Biological

Registry Number: 0

Grant and Affiliation Information for Proteomics analysis in lung cancer: challenges and opportunities.

AFFILIATION: Vanderbilt Ingram Cancer Center, Nashville, Tennessee 37232, USA.

Country: Australia

AGENCY: United States NCI

GRANT: P50 CA90949

ACRONYM: CA

MEDLINETA: Respirology

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