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- Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. We previously identified mutations in the Lpin1 gene, encoding lipin-1, as the underlying cause of lipodystrophy in the fatty liver dystrophy (fld) mutant...

- Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR. In structural genomics centers, nuclear magnetic resonance (NMR) screening is in increasing use as a tool to identify folded proteins that are promising...

- Trichorrhexis nodosa and amino acid metabolism.

- Triple resonance experiments for aligned sample solid-state NMR of (13)C and (15)N labeled proteins. Initial steps in the development of a suite of triple-resonance (1)H/(13)C/(15)N solid-state NMR experiments applicable to aligned samples of (13)C and (15)N...

- Tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence. This paper critically reviews analytical applications of the chemiluminescence from tris(2,2'-bipyridyl)ruthenium(II) and related compounds published in the...

- Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas. PURPOSE: Pre-existing and acquired drug resistance are major obstacles to the successful treatment of glioblastomas. METHODS: We used an integrated...

- Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo. Twisted gastrulation (TSG) is an extracellular modulator of bone morphogenetic protein (BMP) activity and regulates dorsoventral axis formation in early...

- Ubiquitous and uniform in vivo fluorescence in ROSA26-EGFP BAC transgenic mice. Transplantation studies and cell lineage analyses require the ability to explicitly distinguish morphologically identical cells that have an identifiable...

- Ultrastructural differentiation and enzymatic localization of phosphatases in the developing duodenal epithelium of the mouse. II. The newborn mouse.

- UniRef: comprehensive and non-redundant UniProt reference clusters. MOTIVATION: Redundant protein sequences in biological databases hinder sequence similarity searches and make interpretation of search results difficult....

- Use of an alternative scale-down approach to predict and extend hydroxyapatite column lifetimes. Ceramic hydroxyapatite (CHT) chromatography offers unique selectivity for protein purification. However, columns composed of CHT, a crystalline form of...

- Using electron microscopy to understand functional mechanisms of chromosome alignment on the mitotic spindle.

- Using microfluidics to observe the effect of mixing on nucleation of protein crystals. This paper analyzes the effect of mixing on nucleation of protein crystals. The mixing of protein and precipitant was controlled by changing the flow rate in...

- Using photoinduced charge transfer reactions to study conformational dynamics of biopolymers at the single-molecule level. This mini-review describes how single-molecule sensitive fluorescence resonance energy transfer (FRET) and photoinduced electron transfer (PET) reactions can...

- Variations in the enzymatic properties of human complement subcomponent C1s by treatment with human plasma kallikrein. We have investigated the effect of plasma kallikrein digestion upon hydrolytic activities of human C1s. Incubation of C1s (85 kDa) with plasma kallikrein led...

- Weak alignment of paramagnetic proteins warrants correction for residual CSA effects in measurements of pseudocontact shifts. Paramagnetic metal ions can induce molecular alignment with respect to the magnetic field. This alignment generates residual anisotropic chemical shifts...

- When it comes to couple(r)s, do opposites attract?

- [A historical perspective on familial cancer]

- [A study of conformational changes in proteins by gel filtration]

- [Aldosterone-stimulating factor, a newly discovered factor in blood volume and pressure control]