Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG.

Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Research Abstract Details 

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Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Abstract Text:

Approximately 15 per cent of the total IgG in normal rabbit serum reacted with protein A. When this protein reactive IgG fraction was treated with acid at pH 2.7 and then digested with plasmin, thus splitting the rabbit IgG between the CH2 and CH3 domains, both the isolated Facb and the pFc' fragments were protein A non-reactive. This results indicates that at least one intact Fc chain is necessary to fulfil the protein A-fc interaction. Traces of protein A reactive rabbit F(ab')2 fragments isolated from normal IgG were also found. These fragments mixed with normal rabbit IgG precipitated protein A.

Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Publishing Authors By Initials

For similar proteins: bacterial proteins: staphylococcal protein a research abstracts see: proteins: bacterial proteins: staphylococcal protein a research

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Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica et microbiologica Scandinavica. S

VOLUME: 86C

Page Numbers: 211-4

Journal Abbreviation:

ISSN: 0304-1328

DAY: 26

MONTH: Oct

YEAR: 1978

Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7508469

Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Keywords Mesh Terms:

KEYWORDS: Staphylococcal Protein A

MESH TERMS: immunology

Chemical & Substance for Abstract: Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG. Information

Substance Name: Plasmin

Registry Number: EC 3.4.21.7

Grant and Affiliation Information for Protein A reactivity of whole rabbit IgG and of fragments of rabbit IgG.

AFFILIATION:

Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Scand [C

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