Prostate cancer is the most common malignancy in men and, as a result, there has been a nationwide emphasis on screening and detection. With the widespread use of the prostate-specific antigen (PSA), prostate cancer screening effectively detects localized prostate cancer. However, recent reports have identified a significant proportion of prostate cancer in men with low PSA levels. Many of these cancers are higher-grade malignancies. Consequently, PSA may function more effectively as a screening tool when applied over a continuum that is associated with degree of risk, rather than a binary measure. Other markers are currently being investigated. Ideally, a marker will identify the malignancy that is a clinical threat, thereby avoiding intervention for indolent disease. Prevention strategies may be employed for higher-risk patients, and these strategies eventually may be tailored to genetic or other risks.
Prostate cancer detection strategies. Publishing Authors By Initials
Prostate cancer detection strategies. Journal Published:
PUBLICATION TYPE: Review
Journal: Current urology reports
VOLUME: 7
Page Numbers: 181-5
Journal Abbreviation:
ISSN: 1527-2737
DAY: 3
MONTH: May
YEAR: 2006
Prostate cancer detection strategies. Information
Number of References: 60
LANGUAGE: eng
NlmUniqueID: 100900943
Prostate cancer detection strategies. Keywords Mesh Terms:
KEYWORDS: Prostatic Neoplasms
MESH TERMS: genetics
Chemical & Substance for Abstract: Prostate cancer detection strategies. Information
Substance Name: Prostate-Specific Antigen
Registry Number: EC 3.4.21.77
Grant and Affiliation Information for Prostate cancer detection strategies.
AFFILIATION: Department of Urology, University of Texas Health Science Center, Mail Code 7845, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. brandt2@uthscsa.edu
Country: United States
AGENCY: United States NCI
GRANT: 5U01 CA 86402
ACRONYM: CA
MEDLINETA: Curr Urol Rep
REFSOURCE:
DATABASENAME:
ACCESSION NUMBER:
Number Hits: 0
Prostate cancer detection strategies Related Publications