The efficiency of Proproten-100 containing antibodies to S100 protein in ultralow doses and used to relieve somatovegetative and psychoneurological manifestations of the alcohol withdrawal syndrome was studied in a double-blind, placebo-controlled clinical trial. The preparation possessed anxiolytic, sedative, hypnagogic, and vegetostabilizing properties. Proproten-100 more rapidly relieved the alcohol withdrawal syndrome than standard drugs (by 2 times). Proproten-100 may used in combination with detoxicating and symptomatic drugs to treat patients with severe disorders. The preparation did not cause side effects. Our observations indicate that Proproten-100 may be used alone (monotherapy) or in combination with standard pharmaceutics for treatment of patients with the alcohol withdrawal syndrome.
Proproten-100 in the therapy of patients with the alcohol withdrawal syndrome. Publishing Authors By Initials
Proproten-100 in the therapy of patients with the alcohol withdrawal syndrome. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Bulletin of experimental biology and medicine
VOLUME: 135 Suppl 1
Page Numbers: 167-70
Journal Abbreviation: Bull. Exp. Biol. Med.
ISSN: 0007-4888
DAY: 1
MONTH: 09
YEAR: 2003
Proproten-100 in the therapy of patients with the alcohol withdrawal syndrome. Information
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LANGUAGE: eng
NlmUniqueID: 372557
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AFFILIATION: Moscow Institute of Psychiatry, Russian Ministry of Health; Russian State Medical University; Russian Medical Academy of Postgraduate Education, Russian Ministry of Health; "Materia Medica Holding" Research-and-Production Company, Moscow.
Country: United States
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MEDLINETA: Bull Exp Biol Med
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