This review focuses on recent developments in helper-dependent adenoviral technology and preclinical studies for helper-dependent adenovirus-mediated liver- and lung-directed gene therapy. Studies highlighting the tremendous potential of these vectors are reviewed, together with some important obstacles that will need to be addressed before clinical utility.
Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy. Publishing Authors By Initials
Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy. Journal Published:
PUBLICATION TYPE: Review
Journal: Current opinion in molecular therapeutics
VOLUME: 8
Page Numbers: 446-54
Journal Abbreviation: Curr. Opin. Mol. Ther.
ISSN: 1464-8431
DAY: 3
MONTH: Oct
YEAR: 2006
Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy. Information
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LANGUAGE: eng
NlmUniqueID: 100891485
Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy. Keywords Mesh Terms:
KEYWORDS: Lung Diseases
MESH TERMS: therapy
Chemical & Substance for Abstract: Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy. Information
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Grant and Affiliation Information for Progress towards the clinical application of helper-dependent adenoviral vectors for liver and lung gene therapy.
AFFILIATION: Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza T619, Houston, TX 77030, USA.
Country: England
AGENCY: United States NHLBI
GRANT: P50 HL59314
ACRONYM: HL
MEDLINETA: Curr Opin Mol Ther
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