[Production of chimeras by embryo microsurgery and their possible application in cattle breeding]

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Abstract Text:

An important contribution to genetic and embryonic engineering in mammalian embryos is the production of chimeric mammals. Chimeras can be produced by aggregating the blastomeres of two different embryos to make a single individual. A method is described to produce bovine chimeras by aggregating non-surgically collected embryos of different breeds and transferring the aggregated embryos nonsurgically to synchronised recipients. An overt chimeric bull calf (Holstein-Friesian and Brown-Swiss) was born on March 31st, 1984. Chimeras have many uses in research, but one practical use is to rescue defective embryos that would not develop to term on their own. Such embryos can be aggregated with normal blastomeres to produce a chimera. Some of the initially defective cells can even become part of the germ line in the chimera and give rise to perfectly normal eggs or sperm. Two models for using this technique in cattle research are described. The lethal disorder arachnomelie has a rather high frequency in some German Brown-Swiss populations. Chimeric calves developing from embryos descending of carrier matings could help to find out the genetic and developmental background of this disorder. Chimeras produced of transgenic teratocarcinoma cell lines and normal embryos offer one possibility to produce transgenic cattle. The advantages and disadvantages of these possibilities are discussed.

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Publishing Authors By Initials

For similar embryonic structures: morula research abstracts see: embryonic structures: morula research

PUBMED ID PMID:

MEDLINE DATE:

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Tierärztliche Praxis. Supplement

VOLUME: 1

Page Numbers: 50-7

Journal Abbreviation:

ISSN: 0930-6447

DAY: 4

MONTH: 03

YEAR: 1985

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Information

Number of References:

LANGUAGE: ger

NlmUniqueID: 9012743

[Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Keywords Mesh Terms:

KEYWORDS: Morula

MESH TERMS: veterinary

Chemical & Substance for Abstract: [Production of chimeras by embryo microsurgery and their possible application in cattle breeding] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [Production of chimeras by embryo microsurgery and their possible application in cattle breeding]

AFFILIATION:

Country: GERMANY

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Tierarztl Prax Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Production of chimeras by embryo microsurgery and their possible application in cattle breeding Related Publications

• Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model.
• Antiangiogenesis treatment for glioblastoma multiforme: challenges and opportunities.
• Blinded comparison of computer-aided detection with human second reading in screening mammography: the importance of the question and the critical numbers game.
• Case of Paroxysmal Hemoglobinuria Treated with Salvarsan.
• Editorial for "Mammography Screening of Women in Their Forties : the impact of changes in screening guidelines".
• Effects of different cryoprotectants and carbohydrates on freezing of matured and unmatured bovine oocytes.
• Electrofusion parameters for mouse two-cell embryos.
• Endogenous inhibitors (GALFs) of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2: derivatives of adrenally produced corticosterone and cortisol.
• Fertilization of bovine oocytes induced solely with combined laser microbeam and optical tweezers.
• Hemorrhagic vestibular schwannoma: an unusual clinical entity. Case report.
• Human VNTR sequences in porcine HTF-islands.
• Human renal 11beta-hydroxysteroid dehydrogenase 1 functions and co-localizes with COX-2.
• Infarcted lactating adenoma presenting as a rapidly enlarging breast mass.
• Influence of beta-carotene on fertility in rabbits when using embryo transfer programs.
• Interstitial chemotherapy with sustained-release polymer systems for the treatment of malignant gliomas.
• Lobular carcinoma in situ of the breast presenting as a mass.
• Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model.
• Mammographic appearance of lymphedema in a TRAM-reconstructed breast.
• PRESIDENT'S ADDRESS ANNUAL MEETING LOS ANGELES COUNTY MEDICAL ASSOCIATION DECEMBER 15, 1921-GOVERNMENTAL ACTIVITIES AND TENDENCIES IN THE HEALTH FIELD.
• Pitfall of MR in a patient with spinal ependymoma and drop metastasis.
• Stereotactic vacuum-assisted breast biopsy: an unusual cause of Mondor's disease.
• THE PLACE OF PATHOLOGY IN THE PRACTICE OF MEDICINE.
• The porcine PHIcDNA linked to the halothane gene detects a NotI RFLP in normal and malignant hyperthermia susceptible pigs.
• Use of Gliadel (BCNU) Wafer in the Surgical Treatment of Malignant Glioma: A 10-Year Institutional Experience.
• Using gene transcription patterns (bar coding scans) to guide wound debridement and healing.
• Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells.
• [Embryo transfer in swine in relation to a gene transfer program]
• [Production of chimeras by embryo microsurgery and their possible application in cattle breeding]
• [The structure of eukaryotic genes]
• [Treatment of knee osteoarthritis]