Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Abstract Text:

Krisztina Toth,Tina L Amyes,Bryant M Wood,Kui Chan,John A Gerlt,John P Richard,

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Publishing Authors By Initials

K Toth,TL Amyes,BM Wood,K Chan,JA Gerlt,JP Richard,

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidine nucleotides: uracil nucleotides: uridine monophosphate research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidine nucleotides: uracil nucleotides: uridine monophosphate research

PUBMED ID PMID:

MEDLINE DATE:

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of the American Chemical Society

VOLUME: 129

Page Numbers: 12946-7

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 5

MONTH: 10

YEAR: 2007

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Keywords Mesh Terms:

KEYWORDS: Uridine Monophosphate

MESH TERMS: metabolism

Chemical & Substance for Abstract: Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Information

Substance Name: Orotidine-5'-Phosphate Decarboxylase

Registry Number: EC 4.1.1.23

Grant and Affiliation Information for Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.

AFFILIATION: Department of Chemistry, University at Buffalo, Buffalo, New York 14260, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM65155

ACRONYM: GM

MEDLINETA: J Am Chem Soc

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate Related Publications

• A novel GJA 1 mutation in oculo-dento-digital dysplasia with curly hair and hyperkeratosis.
• A simple method to determine kinetic deuterium isotope effects provides evidence that proton transfer to carbon proceeds over and not through the reaction barrier.
• A transition state analog for phosphate diester cleavage catalyzed by a small enzyme-like metal ion complex.
• An optimised methodology for the neurobehavioural assessment in rodents.
• Claisen-type addition of glycine to a pyridoxal iminium ion in water.
• Coming out to care: caregivers of gay and lesbian seniors in Canada.
• Covalent catalysis by pyridoxal: evaluation of the effect of the cofactor on the carbon acidity of glycine.
• Dissection of a genetic locus influencing renal function in the rat and its concordance with kidney disease loci on human chromosome 1q21.
• Energy expenditure: a critical determinant of energy balance with key hypothalamic controls.
• Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion.
• Foamy Virus Vectors Expressing Anti-HIV Transgenes Efficiently Block HIV-1 Replication.
• Identification in the mould Hypocrea jecorina of a gene encoding an NADP(+): d-xylose dehydrogenase.
• Improvement of VO2max by cardiac output and oxygen extraction adaptation during intermittent versus continuous endurance training.
• Inhibition of humic substances mediated photooxygenation of furfuryl alcohol by 2,4,6-trimethylphenol. Evidence for reactivity of the phenol with humic triplet excited states.
• Malignant proliferating pilar tumors arising in KID syndrome: a report of two patients.
• Phenotypic Correction of alpha-Sarcoglycan Deficiency by Intra-arterial Injection of a Muscle-specific Serotype 1 rAAV Vector.
• Practical identifiability of photophysical parameters in photodynamic therapy.
• Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.
• Rational design of transition-state analogues as potent enzyme inhibitors with therapeutic applications.
• Some major mycotoxins and their mycotoxicoses-An overview.
• Targeting the RNA-binding protein Sam68 as a treatment for cancer?
• The motivational interview.
• The motivational interview: In practice.
• Topical tacrolimus treatment for chronic dermatitis of the ear.
• Use of local area facilities for involvement in physical activity in Canada: insights for developing environmental and policy interventions.
• When does an intermediate become a transition state? Degenerate isomerization without competing racemization during solvolysis of (S)-1-(3-nitrophenyl)ethyl tosylate.
• Winning the battle for standardization. The U.S. Army Medical Department examines the EMR to develop a standardized process for medication reconciliation documentation.
• [Carbon dioxide laser therapy for anogenital warts in children.]
• [The lessons of Cleopatra or reflections on conter-transfer and borderlines.]
• [The prevalence of bilateral malignant uveal melanoma]