Primary nephrotic syndrome during childhood in Turkey.

Primary nephrotic syndrome during childhood in Turkey. Research Abstract Details 

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Primary nephrotic syndrome during childhood in Turkey. Abstract Text:

BACKGROUND: Minimal change nephrotic syndrome (MCNS) is the most common cause of primary nephrotic syndrome (NS) during childhood. However, recent studies from different countries have reported an increasing incidence of focal segmental glomerulosclerosis (FSGS) in children. METHODS: This is a retrospective study in which 392 Turkish children who were diagnosed with NS during the last 10 years and were followed for at least 2 years, were evaluated. Mean age of the study group was 4.6 +/- 3.4 years (range 0.9-16 years) and 232 were male and 160 were female. RESULTS: In total, 280 patients were diagnosed as MCNS with their initial presentations, laboratory features, and clinical course. Kidney biopsy was performed in the remaining 112 children according to current recommendations. The results showed that membranoproliferative glomerulonephritis (MPGN) was the most common histopathologic diagnosis, 38 (34%) of the 112 patients were found to have MPGN. The number diagnosed as FSGS was 26 (23%). A significant difference was found between the age groups for both MPGN and FSGS, the former being more common in children >6 years of age and the latter more frequent in children

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Primary nephrotic syndrome during childhood in Turkey. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatrics international : official journal of the

VOLUME: 46

Page Numbers: 436-8

Journal Abbreviation: Pediatr Int

ISSN: 1328-8067

DAY: 21

MONTH: Aug

YEAR: 2004

Primary nephrotic syndrome during childhood in Turkey. Information

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LANGUAGE: eng

NlmUniqueID: 100886002

Primary nephrotic syndrome during childhood in Turkey. Keywords Mesh Terms:

KEYWORDS: Turkey

MESH TERMS: epidemiology

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Grant and Affiliation Information for Primary nephrotic syndrome during childhood in Turkey.

AFFILIATION: Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey.

Country: Australia

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MEDLINETA: Pediatr Int

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