Primary aldosteronism: cardiovascular, renal and metabolic implications.

Primary aldosteronism: cardiovascular, renal and metabolic implications. Research Abstract Details 

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Primary aldosteronism: cardiovascular, renal and metabolic implications. Abstract Text:

Gian-Paolo Rossi,Leonardo A Sechi,Gilberta Giacchetti,Vanessa Ronconi,Pasquale Strazzullo,John W Funder,

For many years primary aldosteronism was considered a relatively benign form of hypertension. This assumption reflects the primacy accorded to elevated levels of angiotensin in terms of deleterious cardiovascular effects, and the fact that in primary aldosteronism renin and angiotensin levels are low. We now know that primary aldosteronism causes a constellation of cardiovascular, renal and metabolic sequelae which make it far from benign and that these are not merely effects of blood pressure elevation. In primary aldosteronism, tissue damage, on several indices, is higher than in age-, sex- and blood pressure-matched controls, reflecting the ability of inappropriately elevated aldosterone for salt status to produce structural and functional changes over and above those produced by high blood pressure.

Primary aldosteronism: cardiovascular, renal and metabolic implications. Publishing Authors By Initials

GP Rossi,LA Sechi,G Giacchetti,V Ronconi,P Strazzullo,JW Funder,

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Primary aldosteronism: cardiovascular, renal and metabolic implications. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Trends in endocrinology and metabolism: TEM

VOLUME: 19

Page Numbers: 88-90

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ISSN: 1043-2760

DAY: 7

MONTH: 03

YEAR: 2008

Primary aldosteronism: cardiovascular, renal and metabolic implications. Information

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LANGUAGE: eng

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AFFILIATION: DMCS - Clinica Medica 4 and University of Padua, 35126, Padua, Italy.

Country: United States

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MEDLINETA: Trends Endocrinol Metab

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