Prevention and treatment of vivax malaria.

Prevention and treatment of vivax malaria. Research Abstract Details 

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Prevention and treatment of vivax malaria. Abstract Text:

J Kevin Baird,Eli Schwartz,Stephen L Hoffman,

Plasmodium vivax is a significant public health threat throughout most of the tropics and to travelers to these regions. The infection causes a debilitating febrile syndrome that often recurs and in rare cases ends in death. The complex life cycle of the parasite compounds the difficulty of prevention and treatment, principally due to the phenomenon of relapse. Most commonly used drugs for preventing malaria fail to prevent late relapses by this parasite. Treatment requires dealing with both blood and liver stages. Since 1950, primaquine has been the only drug available for treatment of liver stages, and important clinical questions surround its appropriate use (ie, dosing, efficacy, safety, and tolerability). Likewise, chloroquine has been first-line therapy for vivax malaria since 1946, and the emergence of resistance to the drug further complicates therapeutic management decisions.

Prevention and treatment of vivax malaria. Publishing Authors By Initials

JK Baird,E Schwartz,SL Hoffman,

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Prevention and treatment of vivax malaria. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Current infectious disease reports

VOLUME: 9

Page Numbers: 39-46

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ISSN: 1523-3847

DAY: 26

MONTH: Jan

YEAR: 2007

Prevention and treatment of vivax malaria. Information

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LANGUAGE: eng

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AFFILIATION: ALERTAsia Foundation, c/o Eijkman Institute for Molecular Biology, Jalan Diponegoro No. 69, Menteng, Jakarta 10430, Indonesia.E-mail: kbaird@alertasia.org.

Country: United States

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MEDLINETA: Curr Infect Dis Rep

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