Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico.

Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Research Abstract Details 

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Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Abstract Text:

R M Viani,K Hsia,P Hubbard,J Ruiz-Calderon,R Lozada,J Alvelais,M Gallardo,S A Spector,

At Tijuana General Hospital, between March 2003 and June 2005, pregnant women and other adults, recently identified as HIV infected, antiretroviral naïve, were enrolled to examine the prevalence of primary HIV drug resistance. All subjects had the Calypte HIV-1 BED Incidence enzyme immunoassay test to identify recent infection. Genotypic analysis of HIV-1 protease and reverse transcriptase regions in plasma was performed. Forty-six subjects participated, eight (17%) men, 38 (83%) women. Ten (22%) subjects were classified as having recent HIV infection. HIV genotype was performed in 41 subjects. One subject (2.5%) had a major mutation in the reverse transcriptase region (K219Q) conferring zidovudine resistance, one had a minor mutation at V118I (2.5%) and two subjects (5%) had minor mutation (V179D) associated with non-nucleoside reverse transcriptase inhibitor resistance. There were no major protease inhibitor-associated mutations but minor mutations were common. The prevalence of primary HIV drug resistance in Baja California is low.

Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Publishing Authors By Initials

RM Viani,K Hsia,P Hubbard,J Ruiz-Calderon,R Lozada,J Alvelais,M Gallardo,SA Spector,

For similar bacterial infections and mycoses: infection: pregnancy complications, infectious research abstracts see: bacterial infections and mycoses: infection: pregnancy complications, infectious research

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Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: International journal of STD & AIDS

VOLUME: 18

Page Numbers: 235-8

Journal Abbreviation:

ISSN: 0956-4624

DAY: 3

MONTH: Apr

YEAR: 2007

Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Information

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LANGUAGE: eng

NlmUniqueID: 9007917

Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Keywords Mesh Terms:

KEYWORDS: Pregnancy Complications, Infectious

MESH TERMS: genetics

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Grant and Affiliation Information for Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico.

AFFILIATION: Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093-0672, USA. rviani@ucsd.edu

Country: England

AGENCY: United States NCMHD

GRANT: P60 MD00220

ACRONYM: MD

MEDLINETA: Int J STD AIDS

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