Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey.

Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey. Research Abstract Details 

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Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey. Abstract Text:

Maria Claudia Nascimento,Philippe Mayaud,Ester Cerdeira Sabino,Katia Luz Torres,Silvia Franceschi,Maria Claudia Nascimento,Philippe Mayaud,Ester Cerdeira Sabino,Katia Luz Torres,Silvia Franceschi,

Little data are available on the seroprevalence of, and risk factors for hepatitis B and C viruses (HBV and HCV) infection in Latin American countries. A multi-center serosurvey was conducted among 3,598 first-time blood donors (65% men) from Sao Paulo, Salvador and Manaus in Brazil. The gender-specific seroprevalences of antibodies against hepatitis B core antigen (anti-HBc) and of the hepatitis B surface antigen (HBsAg) in anti-HBc-positive sera were measured, and risk factors analyzed by gender. The gender-specific seroprevalences of antibodies against HCV (anti-HCV) were measured, but risk factors for HCV were not determined. Anti-HBc and HBsAg seroprevalences were not significantly different in men [101/2,341 (4.31%) and 4/2,229 (0.18%), respectively] and women [65/1,237 (5.25%) and 8/1,169 (0.68%), respectively], whereas the seroprevalence of anti-HCV was higher in women (12/1,238 [0.97%] vs. 9/2,353 [0.38%]; odds ratio [OR] = 2.49; 95% confidence interval [CI]: 1.0-6.0). No significant difference for HBV infection was found across the three study sites or by ethnic group. The seroprevalence of anti-HBc increased with age, but decreased with education level in both genders. Lifetime number of sexual partners was associated with anti-HBc prevalence among men (OR = 1.95; 95% CI: 1.2-3.1), but not women. The seroprevalence of HBV and HCV was low among Brazilian blood donors, and exposure increased with age in both genders.

Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey. Publishing Authors By Initials

MC Nascimento,P Mayaud,EC Sabino,KL Torres,S Franceschi,MC Nascimento,P Mayaud,EC Sabino,KL Torres,S Franceschi,

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Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of medical virology

VOLUME: 80

Page Numbers: 53-7

Journal Abbreviation: J. Med. Virol.

ISSN: 0146-6615

DAY: 6

MONTH: Jan

YEAR: 2008

Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: a multi-center serosurvey. Information

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LANGUAGE: eng

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AFFILIATION: Laboratório de Virologia do Instituto de Medicina Tropical, Departamento de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil. nascimentoc@iarc.fr

Country: United States

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MEDLINETA: J Med Virol

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