Preterm labour. Cervical function and prematurity.

Preterm labour. Cervical function and prematurity. Research Abstract Details 

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Preterm labour. Cervical function and prematurity. Abstract Text:

Jane E Norman,

The cervix maintains the fetus in situ during pregnancy and dilates during labour to allow delivery of the baby. Congenital or iatrogenically-induced structural abnormalities of the cervix are associated with an increased risk of preterm birth. The role of cervical infection is less clear. Cervical studies may be useful in the prediction of preterm delivery: both a shortened cervical length identified on transvaginal ultrasound examination and an increased level of fetal fibronectin in cervico-vaginal secretions are associated with an increased risk of preterm delivery. In singleton pregnancy, cervical cerclage reduces the risk of preterm birth by 25%. There is no evidence of a reduction in neonatal mortality or morbidity, and the beneficial effects of preterm birth reduction have to be set against the increased risk of maternal infection. Neither the American College of Obstetricians and Gynecologists (ACOG) nor the Royal College of Obstetricians and Gynaecologists (RCOG) has unequivocally endorsed cervical cerclage. Further work is required to define the role of the cervix in prediction and prevention of spontaneous preterm birth.

Preterm labour. Cervical function and prematurity. Publishing Authors By Initials

JE Norman,

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Preterm labour. Cervical function and prematurity. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Best practice & research. Clinical obstetrics & gy

VOLUME: 21

Page Numbers: 791-806

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ISSN: 1521-6934

DAY: 8

MONTH: 05

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: University of Glasgow, Division of Developmental Medicine, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland, UK. j.e.norman@clinmed.gla.ac.uk

Country: England

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MEDLINETA: Best Pract Res Clin Obstet Gyn

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