Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery.

Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. Research Abstract Details 

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Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. Abstract Text:

F Boesebeck,J Janszky,C Kellinghaus,T May,A Ebner,F Boesebeck,J Janszky,C Kellinghaus,T May,A Ebner,

OBJECTIVE: To examine the predictive value of demographic data for the seizure outcome after extratemporal epilepsy surgery. METHODS: Eightyone patients who underwent resective extratemporal epilepsy surgery were retrospectively studied concerning (a) age at surgery, (b) onset of epilepsy, (c) duration of epilepsy, (d) number of seizures at the time of presurgical evaluation, (d) number of presurgically tested antiepileptic substances and (f) number of seizure types. The data were correlated to the postoperative seizure outcome after two years. RESULTS: 33 patients (40.7%) were seizure free two years after surgery. Univariate and multivariate analysis revealed that both tumor etiology and low presurgical seizure frequency were independently associated with seizure freedom after epilepsy surgery. The recurrence rate in patients with one or more seizures per day was more than two-fold if compared with patients with fewer seizures. The remaining demographic factors did not show a significant association with seizure outcome in our 81 patients. CONCLUSIONS: Fewer than daily seizures prior to surgery and a tumoral etiology independently increase the likelihood of remaining seizure free two years after extratemporal epilepsy surgery.

Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. Publishing Authors By Initials

F Boesebeck,J Janszky,C Kellinghaus,T May,A Ebner,F Boesebeck,J Janszky,C Kellinghaus,T May,A Ebner,

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Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of neurology

VOLUME: 254

Page Numbers: 996-9

Journal Abbreviation: J. Neurol.

ISSN: 0340-5354

DAY: 8

MONTH: 05

YEAR: 2007

Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery. Information

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LANGUAGE: eng

NlmUniqueID: 423161

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Grant and Affiliation Information for Presurgical seizure frequency and tumoral etiology predict the outcome after extratemporal epilepsy surgery.

AFFILIATION: Bethel Epilepsy Center, Klinik Mara I, Maraweg 21, 33617, Bielefeld, Germany.

Country: Germany

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MEDLINETA: J Neurol

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