Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro.

Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Research Abstract Details 

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Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Abstract Text:

Renfu Quan,Disheng Yang,Xudong Miao,Xiaochun Wu,Hongbin Wang,Wei Li,

To obtain immunocompatibility, graded zirconia-hydroxyapatite (ZrO(2)-HA) composite bioceramic and simplex ZrO(2)-HA composite bioceramic are prepared. Peripheral blood mononuclear cells (PBMCs) harvested from healthy individuals are cultured with the two ceramic extracts to assess their effect on the transformation of lymphocytes, apoptotic ratio, CD69 expression, and expression of cytokine of TNFalpha and IL-6, with or without phytohemoagglutinin (PHA)-stimulated cells. Ceramic extracts did not activate the resting lymphocytes, whereas the response of the PHA-stimulated cells was significantly modified. The PBMCs activated by graded ZrO(2)-HA composite bioceramic is noticeably smaller than that by simplex ZrO(2)-HA composite bioceramic; these results, however can only be seen under the amplified effect of PHA-stimulation.

Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Publishing Authors By Initials

R Quan,D Yang,X Miao,X Wu,H Wang,W Li,

For similar inorganic chemicals: elements: metals, heavy: zirconium research abstracts see: inorganic chemicals: elements: metals, heavy: zirconium research

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MEDLINE DATE:

Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biomaterials applications

VOLUME: 22

Page Numbers: 123-44

Journal Abbreviation:

ISSN: 0885-3282

DAY: 25

MONTH: 10

YEAR: 2006

Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8813912

Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Keywords Mesh Terms:

KEYWORDS: Zirconium

MESH TERMS: toxicity

Chemical & Substance for Abstract: Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro. Information

Substance Name: Zirconium

Registry Number: 7440-67-7

Grant and Affiliation Information for Preparation of graded zirconia hydroxyapatite composite bioceramic and its immunocompatibility in vitro.

AFFILIATION: Department of Orthopaedics, Second Affiliated Hospital, Zhejiang University, 310009 Hangzhou, China.

Country: England

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MEDLINETA: J Biomater Appl

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