Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances.

Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. Research Abstract Details 

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Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. Abstract Text:

Daisuke Obinata,Kenya Yamaguchi,Daisaku Hirano,Toshio Yoshida,Masayoshi Soma,Satoru Takahashi,Daisuke Obinata,Kenya Yamaguchi,Daisaku Hirano,Toshio Yoshida,Masayoshi Soma,Satoru Takahashi,

A 56-year-old woman suffered from severe depression due to Cushing's syndrome with right adrenal adenoma. She had a normal mental state before developing Cushing's syndrome. Because of her depressive state, informed consent for the treatment could not be obtained, and oral administration of 1.5 g/day metyrapone was commenced. After two weeks, her mental state had markedly improved. She subsequently underwent a right adrenalectomy, and metyrapone administration was terminated on the day of surgery. Without modification on the replacement of corticosteroids, the postoperative course was uneventful. Preoperative management of Cushing's syndrome with metyrapone may be useful in cases of severe psychiatric disturbances due to hypercortisolism.

Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. Publishing Authors By Initials

D Obinata,K Yamaguchi,D Hirano,T Yoshida,M Soma,S Takahashi,D Obinata,K Yamaguchi,D Hirano,T Yoshida,M Soma,S Takahashi,

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Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International journal of urology : official journa

VOLUME: 15

Page Numbers: 361-2

Journal Abbreviation: Int. J. Urol.

ISSN: 1442-2042

DAY: 2

MONTH: Apr

YEAR: 2008

Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. Information

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LANGUAGE: eng

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AFFILIATION: Department of Urology, Nihon University School of Medicine, Tokyo, Japan.

Country: Australia

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MEDLINETA: Int J Urol

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