Prenatal cocaine and tobacco effects on children's language trajectories.

Prenatal cocaine and tobacco effects on children's language trajectories. Research Abstract Details 

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Prenatal cocaine and tobacco effects on children's language trajectories. Abstract Text:

Barbara A Lewis,H Lester Kirchner,Elizabeth J Short,Sonia Minnes,Paul Weishampel,Sudtida Satayathum,Lynn T Singer,

OBJECTIVE: The objective of this study was to examine the effects of prenatal cocaine and polydrug exposure on language development of preschool children using a prospective longitudinal model, controlling for confounders. METHODS: Children who were exposed to cocaine in utero (n = 209) and nonexposed children (n = 189) were followed prospectively at birth and at 1, 2, 4, and 6 years of age and were compared on receptive, expressive, and total language scores across time using random coefficient models, controlling for confounders. RESULTS: A significant, stable effect of cocaine exposure on language development was observed over time for all language domains, with cocaine exposure related to poorer language performance. Cigarette exposure was related to lower receptive language scores. Environmental influences on language scores were also observed. Both the cocaine-exposed and nonexposed children declined in language performance over time. CONCLUSIONS: Prenatal cocaine exposure has a stable negative effect on language skills during the first 6 years of life. Both cocaine-exposed and nonexposed children showed decreased language growth over time; however, cocaine-exposed children demonstrated linguistic deficits compared with nonexposed peers and did not catch up. Cigarette and environmental influences were also noted.

Prenatal cocaine and tobacco effects on children's language trajectories. Publishing Authors By Initials

BA Lewis,HL Kirchner,EJ Short,S Minnes,P Weishampel,S Satayathum,LT Singer,

For similar behavior and behavior mechanisms: behavior: habits: smoking research abstracts see: behavior and behavior mechanisms: behavior: habits: smoking research

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Prenatal cocaine and tobacco effects on children's language trajectories. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Pediatrics

VOLUME: 120

Page Numbers: e78-85

Journal Abbreviation: Pediatrics

ISSN: 1098-4275

DAY: 3

MONTH: Jul

YEAR: 2007

Prenatal cocaine and tobacco effects on children's language trajectories. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376422

Prenatal cocaine and tobacco effects on children's language trajectories. Keywords Mesh Terms:

KEYWORDS: Smoking

MESH TERMS: adverse effects

Chemical & Substance for Abstract: Prenatal cocaine and tobacco effects on children's language trajectories. Information

Substance Name: benzoylecgonine

Registry Number: 519-09-5

Grant and Affiliation Information for Prenatal cocaine and tobacco effects on children's language trajectories.

AFFILIATION: Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA. bxl@case.edu

Country: United States

AGENCY: United States PHS

GRANT: NIDA R01-07957

ACRONYM:

MEDLINETA: Pediatrics

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